One of the effects of vibrations resulting from the flow of fluids is the failure that occurs to the structure of the systems, which in turn affects the efficiency of the parts that make up those systems. for the purpose of studying the possibility of improving the performance of the systems, a liquid other than water and coolant (super antifriz\petrol ofisi) was chosen because of its advantages that can be taken advantage of, including the high viscosity of water and its tolerance to high temperatures resulting from combustion or air temperature, as well as low temperatures to ensure the operation of the system, that is, it maintains stability system temperature to obtain the best possible condition In addition to the purity of the liquid from salts and the presence of a percentage of oil in the composition of the coolant, an insulating layer is formed inside the pipes to prevent rust and corrosion in the pipes, thus ensuring the flow of fluids and prolonging the life of the pipes. The aim is to study and analyze the effect of induced vibrations and internal pressure on fluid transport pipes, and to compare them in the cases of using water and coolant under the same conditions. An empirical analysis considering the natural frequencies produced by the effect of fluid pressure under various stabilization conditions. It was observed from the results that the higher the pressure, the greater the percentage of the deflection of the copper tubes compared to the Aluminium tubes when using both liquids (water and coolant) at the same boundary condition noted the percentage of the deflection difference when using copper pipe (from 0% to 20.3%) was less than using Aluminium (from 2% to 59%) when the pressure was increased. That mean the Aluminium pipe better than copper pipe.