Clearances of cages in ball bearings, including pocket and guiding clearances, play a vital role in the stability and reliability of bearings. In this paper, experiments on the cage motion and wear were carried out to investigate the influence of clearances in ball bearings. Firstly, the cages with a series of pocket and guiding clearances were specially designed and tested for prescribed operating conditions on a bearing test rig in which the cage motions were measured, and corresponding wear was also observed. Then, the normalized trajectory, waveform, and spectra of cage motion were constructed and compared to illustrate the effects of clearances on the cage motion and then to establish the relationship between cage motion and wear. Results reveal that the cage motion and wear are both significantly affected by its clearances. The increment of cage guiding clearance makes the whirl trajectories of the cage regular and the motion frequency of cage motion significantly change. However, the increment of cage pocket clearance make the whirl trajectories change from well-defined patterns to complicated ones, and the frequency of cage motion apparently changes. Additionally, the bearing wear is closely related to the cage motion. If the inner ring frequency is of domination for the cage motion, the cage guiding surface will wear seriously. While cage motion is dominated by two times cage frequency in spectrum domain, the cage pocket will wear more seriously.