We investigate the discovery potential of semileptonic hyperon decays in terms of searches of new physics at teraelectronvolt scales. These decays are controlled by a small SU (3)-flavor breaking parameter that allows for systematic expansions and accurate predictions in terms of a reduced dependence on hadronic form factors. We find that muonic modes are very sensitive to non-standard scalar and tensor contributions and demonstrate that these could provide a powerful synergy with direct searches of new physics at the LHC.Introduction.-The meson and baryon semileptonic decays have played a crucial role in the discovery of the V − A structure [1] and quark-flavor mixing [2] of the (charged current) electroweak interactions in the Standard Model (SM). From a modern perspective, high-precision measurements of these decays provide a benchmark to test the SM and complement the direct searches of new physics (NP) at teraelectronvolt (TeV) energies.For example, the accurate determination of the elements V ud and V us of the Cabibbo-Kobayashi-Maskawa (CKM) matrix can be used to test its unitarity, constraining NP with characteristic scales as high as Λ ∼ 10 TeV [3]. Furthermore, one can test the V − A structure of the charged currents in d → u transitions using neutron and nuclear β decays [3][4][5][6][7][8][9] and pion decays [10,11]. Current limits for the associated NP scale are also at the TeV level, and important improvements are expected from future experiments [12]. Searches of non-standard d → u transitions can also be done using LHC data, through e.g. the collision of d and u partons in the pp → e ± + M ET + X channel (where MET stands for missing transverse energy) [12]. This leads to an interesting synergy between low-and high-energy NP searches in these flavor-changing processes.A similar comprehensive analysis of exotic effects in s → u transitions has not been done yet. The (semi)leptonic kaon decays are optimal laboratories for this study due to the intense program of high-precision measurements and accurate calculations of the relevant form factors that has been carried out over the last decades [13]. Indeed, bounds on righthanded [14,15] or scalar and tensor [16] NP interactions at the 10 −2 − 10 −3 level (relative to the SM) can be obtained [17,18]. Generally speaking, (pseudo)scalar and tensor operators modify the spectrum of the decay and a detailed knowledge of the q 2 dependence of the form factors becomes necessary [19].In this letter we investigate the physics potential of the semileptonic hyperon decays (SHD) to search for NP. Although the description of these modes may seem involved due to the presence of six nonperturbative matrix elements or form factors, they present interesting features [20][21][22][23]: (i) In the isospin limit, there are a total of 8 different channels, each having a differential decay rate with a rich angular dis-