Experimental Results on a New Method for Analysis of Heart Rate Variability

Conte, Elio; Giroldini, William; Laterza, Vincenza; Conte, Sergio; Pieralice, M.; Casciaro, Francesco; Luca, Gabriele De; Giuliano, Antonio; Mendolicchio, Leonardo; Todarello, Orlando

doi:10.4236/wjcd.2014.48048

Cited by 5 publications

(14 citation statements)

References 8 publications

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“…Sinus rhythm oscillates around the mean HR, which is dependent on continuous regulation by ANS. Heart rate variability is a predictor that qualitative in charges of heart rate during normal beat to beat in physiological processes of the autonomic nervous system [4]. A number of techniques have been developed to quantify beat-to-beat variability in order to provide indices of cardiac autonomic regulation in both health and disease [5].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Heart Rate Variability Between Patients With Major Depressive Disorder and Normal Subjects

Chompoopan¹

2018

GEOMATE

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Major Depressive Disorder is one of the major mental health problems that affect the quality of life of the patients. The reduced heart rate variability (HRV) and elevated heart rate that associated with depression have been found as risk factors for cardiac mobility and mortality. These patients should be assessed regularly on HRV parameters and compare with those of normal subjects. This study aimed to compare heart rate variability between patients with the major depressive disorder and normal subjects. This study was conducted at a psychiatric department in Khon Kaen University, Srinagarind Hospital, Khon Kaen province, Thailand. A cross-sectional analytic study design was used. Forty patients diagnosed with the major depressive disorder (who had been treated with antidepressants) were matched according to age, gender with 40 normal subjects participated. They were assessed on HRV for time domain (standard deviation normal to normal: SDNN, and the root mean square of successive differences: RMSSD) and frequency domain (High frequency: HF, low frequency: LF, and LF/HF ratio) using SA 3000P Digital. The results showed that The HRV in the patients and in the normal subjects were found with SDNN 28. 60, 31.44; RMSSD 23.78, 26.73; HF 4.70, 5.04; LF 4.46, 5.01; and LF/HF 1.16, 1.35 respectively. However, No significant difference in the HRV variables between MDD and normal subjects except LF. Findings of this study show that HRV in the treated patients with major depressive disorder seems to be a little lower than the normal subjects. This may be due to the effects of well treated with antidepressants. It is suggested that HRV may be one of the outcome measures for this patient population.

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Section: Introductionmentioning

confidence: 99%

Comparison of Heart Rate Variability Between Patients With Major Depressive Disorder and Normal Subjects

Chompoopan¹

2018

GEOMATE

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“…Specifically, in the beat-to-beat RR interval, the variability of such heart rhythm is intrinsic and of fundamental importance. In previous papers we have also shown that it exhibits scale-free characteristics [36] [40]. The conclusion is that scale-free component of the heart rate variability (HRV) is of basic importance.…”

Section: Discussionmentioning

confidence: 99%

The Transcutaneous Vagus Nerve Stimulation Output of the NuCalm Device of Solace Lifesciences Is Found to Be a Multifractal and Therefore It Is Indicated in the Treatment of Heart Rate Variability in the Dysfunction of Autonomic Nervous System in Anxiety, Depression and Stress

Conte¹,

Wang²,

Sala³

et al. 2017

JBBS

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We have investigated the Nu Calm Transcutaneous Vagus Nerve Stimulation device of the NuCalm Solace Lifesciences founding that it gives a multifractal output. A diminishing fractal/multifractal HRV is consistently reported in literature as related to a serious Autonomic Nervous System (ANS) dysfunction that of course we observe in several psychological and psychiatric disorders. Therefore, we suggest the investigators to apply such a device in subjects affected from anxiety, depression and stress using the method of inducing tVNS stimulation.

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“…Consequently, the HRV analysis has entered as standard methodology to be employed as a simple, inexpensive and non-invasive method that provides information on neurocardial integrity. In addition to standard methods based on the use of time linear indexes and Fats Fourier Transform in frequency domain (FFT), recently, we have introduced a new method, called CZF, to evaluate heart rhythm variability in old as well as in young subjects [3]- [5].…”

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confidence: 99%

“…They are the time linear indexes and the FFT or DFT that, as it is well known, is able to give, in addition to the PSD (total Power Spectral Density), substantially three bands, the VLF that relates thermoregulation, hormonal activity and rennin-angiotensin system and, generally speaking, the circadian rhythms, the LF band that relates substantially the orthosympathetic activity (really mixed with parasympathetic components) and the finally the HF band that relates parasympathetic activity and respiration. Soon after we used the CZF method that we indicated previously [3]- [5], The application of this method is so important since, using the same previously VLF, LF, HF bands, estimates this time the variability of the heart rhythm, analyzing variability in heart rhythm between adjacent heart beats and thus giving accurate and quantitative information on the heart modulating ANS activity inducing heart rhythm variability step by step. Soon after we examined also the histograms distribution of the obtained R-R intervals and HR.…”

mentioning

confidence: 99%

“…In Figure 3 and Figure 4, we have the results of application of our CZF method for analysis of variability of Heart Rhythm. We have discussed in detail this method in [3]- [5]. We re-outline here that this method enables us to explore variability in heart rhythm between subsequent beats (one time in absolute value, thus estimating the entity of the variation and one time without absolute value and thus evaluating acceleration and deceleration of the beat).…”

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confidence: 99%

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Heart Rate Variability: On the Importance to Perform HRV Analysis in Subjects Affected from Muscular Dystrophy

Conte¹,

Ware²,

Marvulli³

et al. 2015

WJCD

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This paper discusses a case of muscular dystrophy on which it has been performed HRV analysis. The results that we obtain evidence that the subject delineates a net ANS dysfunction. All the basic parameters relating standard time and frequency domain of HRV analysis result profoundly altered. Examination by Poicaré plot evidences in particular that the subject has an atrial fibrillation. Non linear indexes ApEn and Samp En evidence the very high condition of risk of the subject. The merging indication is for the cardiologist and scholars in cardiovascular disease to perform always ANS investigation in subjects in case of muscular dystrophy. After the NPT treatment, the subject obtains a net improvement.

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Experimental Results on a New Method for Analysis of Heart Rate Variability

Abstract: A new method for HRV analysis is described and experimental results are given.

Cited by 5 publications

References 8 publications

Comparison of Heart Rate Variability Between Patients With Major Depressive Disorder and Normal Subjects

Comparison of Heart Rate Variability Between Patients With Major Depressive Disorder and Normal Subjects

The Transcutaneous Vagus Nerve Stimulation Output of the NuCalm Device of Solace Lifesciences Is Found to Be a Multifractal and Therefore It Is Indicated in the Treatment of Heart Rate Variability in the Dysfunction of Autonomic Nervous System in Anxiety, Depression and Stress

Heart Rate Variability: On the Importance to Perform HRV Analysis in Subjects Affected from Muscular Dystrophy

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