Background: Quasifission is the main reaction channel hindering the formation of superheavy nuclei (SHN). Its understanding will help to optimize entrance channels for SHN studies. Quasifission also provides a probe to understand the influence of shell effects in the formation of the fragments. Purpose: Investigate the role of shell effects in quasifission and their interplay with the orientation of the deformed target in the entrance channel. Methods: 48 Ca+ 249 Bk collisions are studied with the time-dependent Hartree-Fock approach for a range of angular momenta and orientations. Results: Unlike similar reactions with a 238 U target, no significant shell effects which could be attributed to 208 Pb "doubly-magic" nucleus are found. However, the octupole deformed shell gap at N = 56 seems to strongly influence quasifission in the most central collisions.Conclusions: Shell effects similar to those observed in fission affect the formation of quasifission fragments. Mass-angle correlations could be used to experimentally isolate the fragments influenced by N = 56 octupole shell gaps.On the theory side, quasifission has been studied with various approaches. This includes classical methods such as a transport model [34], the dinuclear system model [35][36][37][38], and models based on the Langevin equation [39][40][41][42][43]. Microscopic approaches such as quantum molecular dynamics [44][45][46] and the time-dependent Hartree-Fock (TDHF) theory [17,18,32,43,[47][48][49][50][51][52][53][54][55][56][57] have also been used. See [58][59][60][61] for recent reviews on TDHF.An advantage of microscopic calculations is that their only inputs are the parameters of the energy density functional describing the interaction between the nucleons. Since these parameters are usually fitted on nuclear structure properties only, such calculations do not require additional parameters determined from reaction mechanisms, such as nucleus-nucleus potentials. In addition, TDHF calculations treat both reaction mechanisms and structure properties on the same footing. This is important for reactions with actinide targets which exhibit a strong quadrupole deformation.