The market for dry vacuum pumps is expected to increase in the coming years. Improving the efficiency of these machines requires comprehensive understanding of the flow dynamics within the working chambers. For this purpose, Computational Fluid Dynamics (CFD) is used as it offers better insight of the working process of a screw machine. In this study, a twin-screw vacuum pump with a large helix angle was analysed. This is a challenging case for CFD due to the limitations of grid generation in the transverse plane on the mesh quality. Two types of transverse meshes were generated using the software SCORGTM: casing to rotor non-conformal mesh and casing to rotor conformal mesh. The quality of the mesh in terms of aspect ratio and orthogonality were compared. The casing to rotor conformal mesh was used with ANSYS Fluent in order to obtain performance characteristics of the vacuum pump with the moderate helix angle of 62° such as the mass flow rate, rotor torque, and indicated power. The performance prediction results were satisfactory but the grid quality was relatively low with orthogonality reaching 40° and aspect ratio over 250 in some cases. As the helix angle increases the quality of mesh decreases. This paper presents the new development of a grid generation algorithm which uses the normal rack to map the fluid domain in the normal plane instead of the transverse plane. This new mesh generation method is expected to better align the computational grid with the main and leakage flows in order to significantly improve grid quality and reduce the numerical diffusion in case of screw machines with large helix angles.