Experimental study on electrostatic charging of polymer powders in mixing processes

Comparative Study of the Triboelectric Charging Behavior of Powders Using a Nonintrusive Approach

“…1,2 Subsequent electrostatic discharges from the surfaces of triboelectrically charged powders during powder handling and processing operations such as blending or pneumatic transport could serve as potential ignition sources for dust explosions in flammable atmospheres. 3,4 Besides the hazards involved in triboelectrification, charged powders could cause major processing problems by forming agglomerated and cohesive structures affecting smooth flow, 5,6 mixture homogeneity, 7,8 particle dispersion, and deposition. 9,10 However, electrostatically charged powders can be advantageous in applications such as electrophotography, 11,12 dry powder coatings, 13,14 and electrostatic separation processes.…”

“…Triboelectrification occurs when dissimilar surfaces are rubbed together and then separated, resulting in charge accumulation on the surfaces. , Subsequent electrostatic discharges from the surfaces of triboelectrically charged powders during powder handling and processing operations such as blending or pneumatic transport could serve as potential ignition sources for dust explosions in flammable atmospheres. , Besides the hazards involved in triboelectrification, charged powders could cause major processing problems by forming agglomerated and cohesive structures affecting smooth flow, , mixture homogeneity, , particle dispersion, and deposition. , However, electrostatically charged powders can be advantageous in applications such as electrophotography, , dry powder coatings, , and electrostatic separation processes. , In addition, numerical simulations showed that drug deposition in the lungs can be improved through a combination of controlled breathing, particle size, and charge. − Therefore, in order to optimize the performances of various powder processes, it is important to be able to first characterize and then understand the electrostatic behavior of the powders in these systems.…”

Alginate graft copolymers and alginate–co-excipient physical mixture in oral drug delivery

“…[116] The quality of polymer powder mixing is dependent on size, density, geometry, moisture content, surface texture and electrostatic charging of the solid particles. [117,118] Optimization of a mixing process often faces constraints as qualification of the characteristics of powder particles requires lengthy and multi-step operations. [116] This is particularly marked when the powder mixing involves a wide variety of excipients, in addition to drug.…”

“…The mixture quality of powder has been a common problem faced by industrialists [116] . The quality of polymer powder mixing is dependent on size, density, geometry, moisture content, surface texture and electrostatic charging of the solid particles [117,118] . Optimization of a mixing process often faces constraints as qualification of the characteristics of powder particles requires lengthy and multi‐step operations [116] .…”

The influence of electrostatic properties on the punch sticking propensity of pharmaceutical blends

“…During pharmaceutical powder processing operations, powder particles frequently come into contact with each other and with the walls of the processing equipment and become electrostatically charged by a process known as triboelectrification [1, [25][26][27][28][29][30][31][32][33][34]. Particle triboelectrification has been suggested as a potential cause of punch sticking [32,35], however, little work has been reported in this area.…”