Experimental Validation of VOF Method in Microchannel Flows

Preda, Petruţa; Bran, Alexandra Maria; Voitincu, C.; Balan, Corneliu

doi:10.1109/atee52255.2021.9425121

Cited by 4 publications

(2 citation statements)

References 13 publications

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“…The PDMS base and curing agent were then prepared in a 10:1 ratio. The mixture was degassed and poured on the microchannel mold following heating in the oven at 90 • C for an hour [38,39]. Following this, PDMS was carefully peeled off the mold and drilled at the designated locations for the microfluidic ports.…”

Section: Methodsmentioning

confidence: 99%

Red Blood Cells’ Area Deformation as the Origin of the Photoplethysmography Signal

Evdochim,

Chiriac,

Avram

et al. 2023

Sensors

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The origin of the photoplethysmography (PPG) signal is a debatable topic, despite plausible models being addressed. One concern revolves around the correlation between the mechanical waveform’s pulsatile nature and the associated biomechanism. The interface between these domains requires a clear mathematical or physical model that can explain physiological behavior. Describing the correct origin of the recorded optical waveform not only benefits the development of the next generation of biosensors but also defines novel health markers. In this study, the assumption of a pulsatile nature is based on the mechanism of blood microcirculation. At this level, two interconnected phenomena occur: variation in blood flow velocity through the capillary network and red blood cell (RBC) shape deformation. The latter effect was qualitatively investigated in synthetic capillaries to assess the experimental data needed for PPG model development. Erythrocytes passed through 10 µm and 6 µm microchannel widths with imposed velocities between 50 µm/s and 2000 µm/s, according to real scenarios. As a result, the length and area deformation of RBCs followed a logarithmic law function of the achieved traveling speeds. Applying radiometric expertise on top, mechanical-optical insights are obtained regarding PPG’s pulsatile nature. The mathematical equations derived from experimental data correlate microcirculation physiologic with waveform behavior at a high confidence level. The transfer function between the biomechanics and the optical signal is primarily influenced by the vasomotor state, capillary network orientation, concentration, and deformation performance of erythrocytes.

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Section: Methodsmentioning

confidence: 99%

Red Blood Cells’ Area Deformation as the Origin of the Photoplethysmography Signal

Evdochim,

Chiriac,

Avram

et al. 2023

Sensors

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“…The non-symmetry will be induced to the interface using different flow rates or fluids on the lateral branches. The angle of 30 • is very common in many configurations, e.g., the branches in a respiratory system, and the Y-microchannel configuration used in mixing [21]. Finally, we decided to have the main width of 400 µm and an aspect ratio of 0.125.…”

Section: Benchmark Definition-geometry Descriptionmentioning

confidence: 99%

Investigation of Multiphase Flow in a Trifurcation Microchannel—A Benchmark Problem

2022

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The evolution of an interface between two immiscible liquids in a three-branch symmetric microchannel is numerically and experimentally investigated. The main goals of the paper are to correlate the numeric data with the experimental results for the tested flow case and to assess the quality of the VOF procedure to trace the interface using the Fluent commercial code. The focus of the experiments was to characterize the dynamics of the oil–water interface formed in the vicinity of the bifurcation, at the entrance in the main microchannel of 400 microns width and 50 microns height. The oil core surrounded by water is visualized and micro-PIV measurements are performed in water. Experimental results qualitatively and quantitatively confirm the 3D numerical simulations. We propose the present investigated flow as a benchmark case for the study of the interface in a branching microchannel geometry.

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