Experimentelle Encephalitisstudien

Silberstein, F.

doi:10.1007/bf02618639

Cited by 4 publications

(1 citation statement)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These active materials, called by their discoverers "viruses," and believed by them to be concerned with the production of encephalitis, are not all, as has already been pointed out, of one kind. The virus of Koritschoner (18) certainly, and that of Kobayashi (19) probably, are merely strains of rabic virus, while the virus called Eck (20), by reason of the fact that it was recovered from dogs in which an Eck fistula had been produced, has not yet been identified with a known variety. One can only speculate on the source of these virulent agents.…”

Section: Contradictions In Etiologic Findingsmentioning

confidence: 99%

Epidemic Encephalitis and Simple Herpes

Flexner

1927

Journal of General Physiology

View full text Add to dashboard Cite

The purpose of this paper is to explain the state of our knowledge of the etiology of epidemic encephalitis, and especially to draw a line of demarcation between the established virus of simple herpes and the hypothetical virus of epidemic encephalitis. It had already been shown that the experimental observations on rabbits do no suffice to prove the identity of the herpes with the encephalitis virus. The discussion of the subject in this paper shows that identity cannot be postulated on the basis of the performed guinea pig experiments. Attention has been drawn to the significant fact that there is lack of harmony in the positive results of those investigators who believe that the incitants of epidemic encephalitis have been discovered. An attempt has been made to attribute some of the discrepancies reported by these investigators either to accidental and contaminating microbic agents, or to the uncovering of virulent agents preexisting in a latent state in the animals employed for inoculation, the existence of which was not previously known or suspected. Since past experience leads us to believe in a single incitant for widespread epidemic diseases, it is probable that, when certainly discovered, the microbe of epidemic encephalitis will prove to be simple and not multiple. The direct corollary to this point of view is that up to the present, the etiology of epidemic encephalitis has not been determined.

show abstract

Section: Contradictions In Etiologic Findingsmentioning

confidence: 99%