Experiments with Mixtures: An Update and Bibliography

Product Life Cycle Management: Stages of New Product Development

“…Several drug delivery systems such as emulsions, solutions, syrups, tablets and so on involve the use of multiple components for their development in the final dosage form (Armstrong and James 2006;Cornell 1979Cornell , 1990Doornbos 1981;Snee and Marquardt 1976). In such systems, each component cannot be varied at each level and hence factorial design, CCD, BBD and so on may not be applicable for their optimisation.…”

Experimental Design: Review and Comment

“…The most complete reference for mixture problems is Cornell (1981), which is a readable introduction to the topic and also discusses much of the most recent research. Reviews of this work are also available (Cornell 1973(Cornell ,1979. Although first proposed for gasoline blending experiments, mixture designs have been applied in a wide variety of situations.…”

[Developments in Linear Regression Methodology: 1959-1982]: Discussion

“…The link is, of course, strongest with response surface methodology. Designs for constrained/restricted experimental regions Stone 1969, Dykstra 1971), including mixture experiments (Cornell 1973(Cornell ,1979(Cornell ,1981Snee 1971bSnee ,1981, are of particular concern. Constraints on the design variables often produce irregular experimental regions that can result in correlations among the model terms producing collinearity and all its effects discussed by Hocking.…”