Kidney transplantation is the treatment of choice for patients with end-stage renal disease. Next to the risk of allograft failure, major obstacles for disease-free survival after kidney transplantation comprise a higher incidence of cancers, infection, and cardiovascular (CV) events. Risk factors for adverse clinical outcomes comprise pre-existent comorbidities, the introduction of an immunodeficient status, as well as (lack of) lifestyle changes after transplantation. Indeed, physical inactivity and poor physical fitness are important targets to address in order to improve clinical outcomes after kidney transplantation.
This review summarizes the current evidence on exercise training after kidney transplantation, derived from randomized controlled trials. As much as possible, results are discussed in the perspective of the SONG-Tx core outcomes, which are recently described as critically important outcome domains for trials in KTR.