Exploration of basal diurnal salivary cortisol profiles in middle-aged adults: Associations with sleep quality and metabolic parameters

Lasikiewicz, Nicola; Hendrickx, H.; Talbot, D; Dye, Louise

doi:10.1016/j.psyneuen.2007.10.013

Cited by 101 publications

(82 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Therefore, both of these systems (and their interactions) may be implicated in the increase of fatigue. The CAR has also shown associations with sleep quality, thus, it is possible that poorer sleep quality impacts both the CAR and subsequent feelings of fatigue (Lasikiewicz, Hendrickx, Talbot, & Dye, 2008;Waye, Clow, Edwards, Hucklebridge, & Rylander, 2003). Further research will be required to identify the effects of each unique aspect of the CAR and the physiological mechanisms underlying these associations.…”

Section: Discussionmentioning

confidence: 99%

Exploring day-to-day dynamics of daily stressor appraisals, physical symptoms and the cortisol awakening response

Gartland

O’Connor

Lawton

et al. 2014

Psychoneuroendocrinology

View full text Add to dashboard Cite

Stress is associated with the secretion of cortisol throughout the day, but less is known about the dynamic effects of stress on the cortisol awakening response (CAR). More widely, knowledge of the causal factors and functions of the CAR are also not fully understood. This study explored: (1) the effects of daily stressors on the next day CAR and; (2) the effects of the CAR on same day physical and affective outcomes. Sixty-four participants completed a daily diary, reporting on the occurrence of daily stressors and stress appraisals, physical symptoms, and affect. Cortisol was measured at 0, 15, 30, and 45 minutes after awakening to provide measures of the CAR on 3 consecutive work days. Stress appraisal was found to negatively predict the CAR, such that where stressors were appraised as more stressful (where perceived demands exceeded resources), the CAR increased less the following morning. Furthermore, the CAR significantly predicted same-day physical symptoms such that a lower CAR was associated with more physical symptoms. This study provides evidence for a pathway through which daily stressors may influence physical wellbeing, and highlights the importance of appraisals for future stress-based cortisol research.

show abstract

Section: Discussionmentioning

confidence: 99%

Exploring day-to-day dynamics of daily stressor appraisals, physical symptoms and the cortisol awakening response

Gartland

O’Connor

Lawton

et al. 2014

Psychoneuroendocrinology

View full text Add to dashboard Cite

show abstract

“…Only younger and older adults were tested, whereas flattened cortisol profiles have been observed in participants with a mean age of 46 years (Lasikiewicz et al, 2008). The inclusion of a third middle-aged cohort in this study may have captured more precisely the age at which changes in cortisol rhythm become apparent.…”

Section: Limitationsmentioning

confidence: 99%

Ageing, depression, anxiety, social support and the diurnal rhythm and awakening response of salivary cortisol

Heaney¹,

Phillips²,

Carroll³

2010

International Journal of Psychophysiology

View full text Add to dashboard Cite

The present study compared the cortisol awakening response and diurnal rhythm in 24 young healthy students and 48 community-dwelling older adults. The associations with diurnal cortisol and depression, anxiety and social support were also examined in relation to age. Salivary cortisol was measured over the course of one day: immediately upon awakening, 30 min later, and then 3 h, 6 h, 9 h and 12 h post-awakening. Participants completed a questionnaire measuring symptoms of anxiety and depression and social support was assessed. Older adults exhibited a significantly reduced awakening response, overall cortisol levels, area under the curve (AUC) and diurnal slopes than younger adults, resulting in a flatter diurnal rhythm. Younger adults with higher depression scores had significantly higher overall cortisol and higher levels upon awakening and 30 min postawakening. In the younger adults, anxiety and depression correlated positively with AUC and the cortisol awakening response (CAR). Older adults with lower social support had a reduced AUC where younger adults with lower social support displayed a larger AUC. These findings suggest that the diurnal rhythm and awakening response of salivary cortisol are significantly reduced in older adults and the associations between anxiety, depression and social support and diurnal cortisol vary with age.

show abstract

“…For example, atypical patterns of cortisol secretion characterised by flatter cortisol slopes (Seltzer et al, 2009), greater CAR magnitude (Ruiz-Robledillo & Moya-Albiol, 2013) and hypo-secretion of cortisol across the day (Bella et al, 2011;Seltzer et al, 2010) have been observed in parental caregivers of children with a 5 DD. Moreover, alterations in basal HPA activity have been implicated as one physiological indicator for downstream disease outcomes such as infectious disease (Edwards, Hucklebridge, Clow, & Evans, 2003), cardiovascular pathologies (Seldenrijk, Hamer, Lahiri, Penninx, & Steptoe, 2012) and sleep problems (Lasikiewicz, Hendrickx, Talbot, & Dye, 2008).…”

Section: Introductionmentioning

confidence: 99%

The psychophysiological impact of childhood autism spectrum disorder on siblings

Lovell

Wetherell

2016

Research in Developmental Disabilities

View full text Add to dashboard Cite

Objective: The negative impact of caring for a child with autism spectrum disorder (ASD) on parents' psychophysiological functioning has been widely evidenced. However, siblings, who also face emotional, social and physical challenges associated with having a brother/sister with ASD, have been less widely studied. This study examined the psychophysiological impact of childhood ASD on Siblings of children with ASD experience greater emotional problems and overall depressive symptoms compared with a control group. Interventions that enhance social support, as well as helping siblings better understand the behaviour problems of their brother/sister with ASD, might be effective for alleviating depressive symptoms.

show abstract

Exploration of basal diurnal salivary cortisol profiles in middle-aged adults: Associations with sleep quality and metabolic parameters

Cited by 101 publications

References 53 publications

Exploring day-to-day dynamics of daily stressor appraisals, physical symptoms and the cortisol awakening response

Exploring day-to-day dynamics of daily stressor appraisals, physical symptoms and the cortisol awakening response

Ageing, depression, anxiety, social support and the diurnal rhythm and awakening response of salivary cortisol

The psychophysiological impact of childhood autism spectrum disorder on siblings

Contact Info

Product

Resources

About