“…Based on similarity of amino acid sequences, GH has been classified into 115 families [http://www.cazy.org/], among which GH-5 [Tanabe et al, 2003], -8 [Mitsutomi et al, 1998;Kimoto et al, 2002;Yatsunami et al, 2002;Choi et al, 2004;Kim et al, 2004;Ogura et al, 2006], -46 [Masson et al, 1994[Masson et al, , 1995Akiyama et al, 1999;Shimosaka et al, 2000;Yoon et al, 2000;Lee et al, 2006], -75 [Zhang et al, 2001;Shimosaka et al, 2005;Cheng et al, 2006] and -80 [Park et al, 1999;Yun et al, 2005] are known to have chitosanase activity. Founded on substrate specificity, these chitosanases have been further divided into 3 subclasses [Izume et al, 1992;Fukamizo et al, 1994Fukamizo et al, , 1995.…”