Expression of a Novel PDGF Isoform, PDGF-C, in Experimental Periapical Lesions

LPS-miR-34a-CCL22 axis contributes to regulatory T cell recruitment in periapical lesions

“…The remaining samples were used for quantitative reverse transcription polymerase chain reaction (qRT-PCR). Periapical tissues surrounding the mesial and distal root apices of the first molars were carefully extracted in accordance with previous reports [24,25], rinsed in cold phosphate-buffered saline, freed of clots, and immediately placed in RNAlater TM Storage Solution (SigmaeAldrich, St. Louis, MO, USA).…”

Platelet-rich Fibrin Increases Proliferation and Differentiation of Human Dental Pulp Cells

“…Transforming growth factor (TGF)-b has been implicated in the differentiation of odontoblast-like cells and in pulp tissue repair in vivo (4). A novel platelet-derived growth factor (PDGF) isoform, PDGF-C, was observed and might be involved in the pathogenesis of rat experimental periapical lesions (5). Recently, platelet-rich plasma (6) has shown clinical success in enhancing endodontic regeneration for periapical inflammatory lesion, although the long-term predictability remains questionable, and its anticipated benefits are moderate.…”

Effectiveness of the Proton Pump Inhibitor Omeprazole Associated with Calcium Hydroxide as Intracanal Medication: An In Vivo Study

“…The sample size was established on the basis of previous literature studies data (22,23) and by using the statistical program GraphPad InStat (GraphPad Software Inc, San Diego, CA) for P < .05. Data were subjected to analysis of variance (one-way analysis of variance), followed by Newman-Keuls post hoc test.…”