2008
DOI: 10.1016/j.fsi.2008.07.003
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Expression of immune-regulatory genes in juvenile Chinook salmon following exposure to pesticides and infectious hematopoietic necrosis virus (IHNV)

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Cited by 83 publications
(40 citation statements)
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“…Previous studies have shown that environmental chemicals may inhibit or induce the transcription of immune genes in fish (Eder et al, 2008;Jin et al, 2013). In this study, the transcription of several tested genes (ifn, c1c and il-1b in embryos; il-1b, il-8 and ucp-2 in adult zebrafish livers) was induced by difenoconazole at 4 dpe.…”
Section: Discussionmentioning
confidence: 76%
“…Previous studies have shown that environmental chemicals may inhibit or induce the transcription of immune genes in fish (Eder et al, 2008;Jin et al, 2013). In this study, the transcription of several tested genes (ifn, c1c and il-1b in embryos; il-1b, il-8 and ucp-2 in adult zebrafish livers) was induced by difenoconazole at 4 dpe.…”
Section: Discussionmentioning
confidence: 76%
“…In zebrafish, within the development of embryo, it depends solely on innate immune defense mechanisms [43]. Unfortunately, a number of previous reports indicate that environmental chemicals, bacteria or viruses could induce or inhibit the mRNA expression of innate immune-related cytokines [44,45]. Among of cytokines, IFN, which belongs to the antiviral cytokines, mediates immune and inflammatory responses [46].…”
Section: Discussionmentioning
confidence: 99%
“…They stated that HEX and ATZ at 10µg l −1 exposure had no effect on plasma levels of cortisol, growth hormone (GH), insulin growth factor I (IGF-I). Eder et al (2008) demonstrated that treatment of juvenile Chinook salmon with chlorpyrifos (CP) and esfenvalerate (EV) led to significantly decreased IGF-I transcription in spleen on days 20 and 60, whereas a short-term increase was seen after CP exposure (day 4). The impact of commonly used pesticides, endosulfan and deltamethrin, on the molecular stress level in black tiger shrimp Penaeus monodon, was investigated using classical oxidative stress biomarkers, protein carbonylation profiles, and levels of heat shock proteins.…”
Section: Impact On Gene Expressionmentioning
confidence: 99%