Expression of the PEPT1, CAT, SOD2 and GPX1 genes in the zebrafish intestine supplemented with methionine dipeptide under predation risk

Abstract

A new methionine dipeptide (dl-methionyldl-methionine) product with lower solubility has recently been developed for fish and shrimp to reduce nutrient loss by leaching (Niu et al., 2018).The association of the genetic and embryological characteristics of zebrafish (Danio rerio) transformed this fish into an excellent animal model for investigation of the development, physiology and behaviour of vertebrates (Gates et al., 1999). In fish and in other vertebrates, amino acids are mainly absorbed in the intestine in the form of di-and tripeptides. Small peptides are absorbed into enterocytes by peptide transporter 1 (Pept1), whereas free