Expression profiles of genes associated with immune response and oxidative stress in Atlantic cod, Gadus morhua head kidney leukocytes modulated by live and heat-inactivated intestinal bacteria

Gene expression and TNF-alpha secretion profile in rainbow trout macrophages following exposures to copper and bacterial lipopolysaccharide

“…Furthermore, it was previously found that copper induced GPx transcription in gills of brown trout [36] and in the liver of Pomatoschistus microps [37]. The results currently obtained for GPx expression following exposure to LPS is in agreement with Lazado et al (2010) [38] who reported an increased expression of GPx and catalase in Atlantic cod HKM stimulated in vitro for 24 h with Pseudomonas sp. These results indicate that the antioxidant defences of the cells were activated to counteract the pro-oxidative potential of copper (a redox-active metal), LPS and the mixture of both.…”

Dietary administration of the probiotic SpPdp11: Effects on the intestinal microbiota and immune-related gene expression of farmed Solea senegalensis treated with oxytetracycline

“…GPx, similar to other enzymes such as catalase and superoxide dismutase, regulates the cell oxidative status. Our results are in agreement with those showing increases in the expression of this gene in the cephalic kidney of Gadus morhua and Epinephelus coioides specimens that received a diet supplemented with Pseudomonasand Psycrhobacter[95] and Lactobacillus plantarum[96], respectively. The improvement of the transcription of this gene could be considered protective against the effects of reactive oxidative ions (ROIs)[97] and could prevent the peroxidation of…”

Nutritional impacts on fish mucosa: immunostimulants, pre- and probiotics

“…The foundation of probiotic research is mainly based on a terrestrial perspective, on humans to be specific. This was also supported by several reports in fish that the viability of a number of probiotic candidates did not serve as a limiting factor of their beneficial actions Lazado and Caipang, 2014a;Lazado et al, 2010a;Pan et al, 2008;Salinas et al, 2006). In the early 2000s, Verschuere and colleagues provided a very lengthy yet encompassing definition that states, "probiotic is a live microbial adjunct which has a beneficial effect on the host by modifying the host-associated or ambient microbial community, by ensuring improved use of the feed and enhancing its nutritional value, by enhancing the host response towards diseases, or by improving the quality of its ambient environment" (Verschuere et al, 2000).…”