Exspiratorische Argon-, Kohlensäure- und Sauerstoffdruckkurven

Muysers, K.; Worth, G.M.; Siehoff, F.

doi:10.1159/000192339

Cited by 3 publications

(2 citation statements)

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“…This slope may be altered in cases of uneven distribution. The slope of the C 02 curve is an index of the ratio of the dis tribution of ventilation to perfusion and that of the 0 2 curve of the distribution of the ventilation, perfusion and diffusion [Muysers et al, 1964].…”

Section: Theory Expiratory Gas Concentration Curves and Concept Of MImentioning

confidence: 99%

Expiratory Gas Concentration Curves for Examination of Uneven Distribution of Ventilation and Perfusion in the Lung

Rj¹

1970

Respiration

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Uneven distribution of pulmonary ventilation and perfusion may be studied by continuous recording of the fractional concentration of gases such as He, C0₂, and O₂ during expiration. On the basis of a simple lung model including one balloon and one tube, which may be locally enlarged to a second compartment of a series model with good mixing in each compartment, an exponential function is derived for the exponential part of the expiratory curve. The main parameter, the time constant (T), may be expressed in terms of the minimum radius of curvature (R_min) of the exponential phase. In the simplest case, R_min = 2.598 T. By measuring R_minin helium expiratory curves of normals it is proved that they have no series ventilation in their lungs, if they are in recumbent position at rest.For cases more complex than this model, a study is made of the concentration fronts moving parallel from the alveolar entrances to the mouth. The theory suggests R_min as a diagnostic criterion for the evaluation of centrilobular emphysema.

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Section: Theory Expiratory Gas Concentration Curves and Concept Of MImentioning

confidence: 99%

Expiratory Gas Concentration Curves for Examination of Uneven Distribution of Ventilation and Perfusion in the Lung

Rj¹

1970

Respiration

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“…This discrepancy may be interpreted by distribution disturbances of ventilation, perfusion and diffusion. We therefore tried to correlate several parameters of breathing mechanics and the arterial oxygen pressures with the radii of expiratory argon-pressure curves, which are assumed to be a parameter of ventilatory distribution ratios [Muysers, 1964], …”

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confidence: 99%

Correlation between Parameters of Breathing Mechanics, Respiratory Gases and Blood Gases in Patients with Chronic Bronchial Obstruction

Reinert¹,

Trendelenburg²

1972

Respiration

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The purpose of our study was an investigation on pathophysiological connections between breathing mechanics, distributions of ventilation and perfusion and arterial oxygen pressures in patients with Respiratory gases breathing mechanics, distributions of ventilation and Blood gases perfusion and arterial oxygen pressures in patients with chronic obstructive lung disease. No correlation could be pointed out. Parameters for analyses of this kind haveto be refined.

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Lung function measurements in ventilated patients using a respiratory mass spectrometer

Lotz

Spilker

1975

Pneumologie

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Exspiratorische Argon-, Kohlensäure- und Sauerstoffdruckkurven

Cited by 3 publications

References 0 publications

Expiratory Gas Concentration Curves for Examination of Uneven Distribution of Ventilation and Perfusion in the Lung

Expiratory Gas Concentration Curves for Examination of Uneven Distribution of Ventilation and Perfusion in the Lung

Correlation between Parameters of Breathing Mechanics, Respiratory Gases and Blood Gases in Patients with Chronic Bronchial Obstruction

Lung function measurements in ventilated patients using a respiratory mass spectrometer

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