Extending the cDNA microarray detection system to evaluate genetically modified soybean and traditional soy foods

Chen, Tzy-Li; Prasad, Vandana; Lee, Ching-Hua; Lin, Kuang-Hung; Chiueh, Lih-Ching; Chan, Ming‐Tsair

doi:10.38212/2224-6614.2635

Journal of Food and Drug Analysis

2020

DOI: 10.38212/2224-6614.2635

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Extending the cDNA microarray detection system to evaluate genetically modified soybean and traditional soy foods

Tzy-Li Chen¹,

Vandana Prasad²,

Ching-Hua Lee³

et al.

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Application of nutrigenomics tools in animal feeding and nutritional research

Zduńczyk¹,

Pareek²

2009

J. Anim. Feed Sci.

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The development of nutrigenomic studies has brought about a number of new research tools (transcriptomics, proteomics and metabolomics), which are important in animal nutrition and food research. This review presents an overview on the application of nutrigenomics tools in this scientifi c area. The use of microarray technologies -the main tools of transcriptomics, has allowed new information concerning the physiological effect of different dietary proteins, of omega-3 polyunsaturated fatty acids and dietary conditioning of colon cancer, to be obtained. The use of proteomics tools (mainly two-dimensional electrophoresis) revealed new information concerning the protein composition of egg and poultry meat proteins, the effect of dietary methionine on breast-meat accretion, the toxicity of dioxin and the safe use of transgenic crops in animal nutrition. Metabolomic analysis allowed the detection of changes in the biochemical profi les of plasma and urine from pigs fed different diets and the determination of metabolite profi les in the liver of rats used as an animal model to characterize the toxicity of triazol fungicides. In livestock species, the microarray technology was discussed and reviewed as potential nutrigenomics tools, in context to its economic benefi ts and improvement of the food quality and safety in dairy and meat industries. However, the newly emerged nutrigenomics tools like -gene expression-based biomarker development still poses a major challenge. Finally, latest developments in the standardization of metobolomics data in relation to functional genomics, nutrigenomics and toxicology studies are discussed.

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Application of nutrigenomics tools in animal feeding and nutritional research

Zduńczyk¹,

Pareek²

2009

J. Anim. Feed Sci.

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show abstract

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Extending the cDNA microarray detection system to evaluate genetically modified soybean and traditional soy foods

Cited by 1 publication

References 7 publications

Application of nutrigenomics tools in animal feeding and nutritional research

Application of nutrigenomics tools in animal feeding and nutritional research

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