Extensive upper respiratory tract sarcoidosis

Abstract

Sarcoidosis is a chronic granulomatous disease of unknown aetiology. It can affect any part of the organism, although the lung is the most frequently affected organ. Upper airway involvement is rare, particularly if isolated. Sarcoidosis is a diagnosis of exclusion, established by histological evidence of non-caseating granulomas and the absence of other granulomatous diseases. The authors report a case of a man with sarcoidosis manifesting as a chronic inflammatory stenotic condition of the upper respiratory tract and trachea.

Chronic Laryngotracheal Granulomatous Disease Secondary to Sporothrix schenckii in an Immunocompromised Patient

“…Inflammatory causes include sarcoidosis, amyloidosis, and granulomatosis with polyangiitis (Wegener's Granulomatosis). 10,13,14 Diagnosis of inflammatory etiologies requires tissue biopsy with special staining as well. Other etiologies of diffuse laryngeal erythema include traumatic injury from intubation, vocal abuse, and gastroesophageal reflux disease.…”

Nasopharyngeal sarcoidosis: a clinical case

“…Морфологическим субстратом саркоидоза является эпителиоидноклеточная гранулема -компактное скопление мононуклеарных фагоцитов (макрофагов и эпителиоидных клеток) с наличием гигантских многоядерных клеток, лимфоцитов и гранулоцитов или без них [7].…”