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Sore throat is one of the most common symptoms with which patients seek an appointment with an otorhinolaryngologist, and also serve as the main subjective symptom of infectious and inflammatory diseases of the pharynx. Pain in the throat, making it difficult to swallow, colloquial speech can drastically reduce the quality of life of patients, almost completely turning them off from active personal, work and social life. At the same time, the increase in the intensity of pain in the throat serves as a diagnostic criterion for the growth of the local inflammatory process, leading to its complications (peritonsillitis, paratonsillar abscess, etc.). Given that the main etiopathogenetic factors of the infectious and inflammatory pathology of the throat are viral, bacterial infection and inflammation, antibacterial and anti-inflammatory therapy are the main points of application in the complex treatment of these diseases. The economic and practical inconveniences of the need to purchase a large number of drugs justify the relevance and practical significance of the use of drug release forms, including a combination of etiopathogenetically targeted substances. This article discusses the effectiveness and feasibility of using a combination of NSAIDs and an antiseptic in one preparation. The studied materials allow us to state that the use of both individual components of the drug and its combined composition in the treatment of infectious and inflammatory diseases of the throat is justified, which manifests itself in a fairly quick and complete relief of the symptoms of the disease without complications and side effects of the drug. A comparative evaluation of the effectiveness of mono and complex therapy indicates a significant advantage of complex treatment, which includes two active ingredients of NSAIDs and an antiseptic.

Inverted papilloma (IP) is a benign sinonasal lesion that has a known propensity for recurrence, local aggressiveness and an association with transformation to squamous cell carcinoma. Due to the high rate of recurrence, association with malignancy and a tendency of multicentricity, the surgical approaches to treatment are controversial. Over the years there has been a slow evolution from aggressive (en bloc) resection by lateral rhinotomy to endoscopic techniques. This progress corresponds to the advances that have been made in endoscopic sinus surgery over the past 15 years. Technological advances have allowed the detection of sinonasal IP before its extension beyond the sinonasal region, thus enabling minimally invasive techniques to be used in the treatment of selected cases of IP. In terms of aetiology there is certain evidence that the presence of HPV in IP could be predictive of malignant transformation. Parameters such as hyperkeratosis, squamous epithelial hyperplasia and a high mitotic index are negative prognostic indicators, which could be useful in the future follow-up of patients with IP.

No abstract

The article provides data about benign tumors of nasal cavity (inverted papillomas), considering the principles of this disease etiology and incidence. The work focuses on the diagnostics of neoplasms of other nasal cavity tumors, in particular, CT and MR diagnostics. The methods for surgical treatment of the nasal cavity inverted papilloma are provided. A separate paragraph of the work is devoted to the observations, providing the data of the disease symptoms. The authors describe an example of nasal cavity inverted papilloma treatment from endonasal endoscopic access and its late result.