Sore throat is one of the most common symptoms with which patients seek an appointment with an otorhinolaryngologist, and also serve as the main subjective symptom of infectious and inflammatory diseases of the pharynx. Pain in the throat, making it difficult to swallow, colloquial speech can drastically reduce the quality of life of patients, almost completely turning them off from active personal, work and social life. At the same time, the increase in the intensity of pain in the throat serves as a diagnostic criterion for the growth of the local inflammatory process, leading to its complications (peritonsillitis, paratonsillar abscess, etc.). Given that the main etiopathogenetic factors of the infectious and inflammatory pathology of the throat are viral, bacterial infection and inflammation, antibacterial and anti-inflammatory therapy are the main points of application in the complex treatment of these diseases. The economic and practical inconveniences of the need to purchase a large number of drugs justify the relevance and practical significance of the use of drug release forms, including a combination of etiopathogenetically targeted substances. This article discusses the effectiveness and feasibility of using a combination of NSAIDs and an antiseptic in one preparation. The studied materials allow us to state that the use of both individual components of the drug and its combined composition in the treatment of infectious and inflammatory diseases of the throat is justified, which manifests itself in a fairly quick and complete relief of the symptoms of the disease without complications and side effects of the drug. A comparative evaluation of the effectiveness of mono and complex therapy indicates a significant advantage of complex treatment, which includes two active ingredients of NSAIDs and an antiseptic.

Introduction. In recent years, the world has seen an increase in the number of patients with difficulty in nasal breathing due to nasal obstruction, one of the causes of which are functional disorders of the nasal mucosa in various forms of rhinitis. Frequent use of intranasal decongestants among the population further contributes to the lack of effectiveness of conservative treatment and the need for surgical correction to restore free nasal breathing. This article discusses the possibility of using a homeopathic preparation containing calendula, witch hazel, aesculus, menthol and zinc oxide in patients with nasal obstruction in vasomotor and chronic subatrophic rhinitis to stop the clinical manifestations of the disease and improve the quality of life of patients.   Аim. Тo evaluate the effectiveness of a drug containing calendula, witch hazel, aesculus, menthol and zinc oxide in patients with vasomotor and chronic subatrophic rhinitis in the complex treatment of nasal obstruction.   Мaterials and methods. The study involved 48 adult patients of both sexes, aged 20 to 50 years, diagnosed with vasomotor (idiopathic) rhinitis in 24 and chronic subatrophic rhinitis in 24 patients. The studied preparation containing calendula, witch hazel, esculus, menthol and zinc oxide was smeared on the mucous membrane of the nasal cavity by laying gauze turundas for 5 minutes, 3 times a day, while the course of treatment was 10 days. The efficacy and safety of the drug was assessed by the dynamics of the severity of subjective symptoms, objective clinical data during control examinations by an otorhinolaryngologist in points, as well as by the presence of side effects in the treatment of the disease.   Results. Results of the study showed a pronounced positive trend in the form of relief of subjective complaints and the main clinical manifestations of the disease, accompanied by an improvement in the quality of life in patients in both groups examined during treatment. Side effects were not observed in patients in both study groups.   Conclusions. Based on the results of the study, conclusions were drawn about the efficacy and safety of using a complex homeopathic preparation containing calendula, witch hazel, esculus, menthol and zinc oxide in an adult group of patients with nasal obstruction, which makes it possible to recommend it for widespread use for the complex treatment of nasal syndrome. obstruction in vasomotor and chronic subatrophic rhinitis, as well as other forms of rhinitis accompanied by nasal obstruction syndrome.

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