SummaryGynoid lipodystrophy (GLD) is a structural, inflammatory, and biochemical disorder of the subcutaneous tissue causing alterations in the topography of the skin. Commonly known as "cellulite," GLD affects up to 90% of women, practically in all stages of the life cycle, beginning in puberty. It is a clinical condition that considerably affects the patients' quality of life. It is a frequent reason for consultation, although the patients resort to empirical, improvised, nonevidence-based treatments which discourage and can be a source of frustration not only because of the lack of results but also due to the complications derived from those treatments. In this article, a panel of experts from different specialties involved in the management of this clinical skin disorder presents the results of a systematic literature search and of the consensus discussion of the evidence obtained from different treatments currently available. The analysis was divided into topical, systemic, noninvasive, and minimally invasive treatments.
ResumenLa lipodistrofia ginoide (LDG) es una alteraci on estructural, inflamatoria y bioqu ımica del tejido subcut aneo que causa modificaciones topogr aficas en la piel. Conocida com unmente como "celulitis", la LDG afecta hasta a 90% de las mujeres, pr acticamente en todas las etapas de la vida, iniciando en la pubertad. Se trata de una condici on que afecta considerablemente la calidad de vida de quien la padece. Es motivo frecuente de consulta aunque las pacientes recurren a tratamientos emp ıri-cos, improvisados, sin bases ni evidencia cient ıfica, los cuales desmotivan y producen frustraci on no s olo por su falta de resultados, sino por complicaciones derivadas de dichos tratamientos. Un grupo de expertos de diversas especialidades involucradas en el manejo de este problema presenta en este art ıculo el resultado de una b usqueda bibliogr afica sistem atica y de la discusi on consensuada de la evidencia obtenida de diversos tratamientos disponibles actualmente. El an alisis se dividi o enThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.