Extraction of glycyrrhizin from licorice using single screw extruder: Process kinetics and stimulus response modeling

Baite, Thangsei Nengneilhing; Das, Amit Baran

doi:10.1080/01496395.2017.1391846

Cited by 10 publications

(3 citation statements)

References 24 publications

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“…It is relatively heat stable and inhibit against the growth of cytopathology for various DNA and RNA viruses. 45,47 Moreover, it is traditionally used for the treatment of cough, sore throat, spleen, bronchitis, allergy, liver, ulcer and kidney. Licorice is also popular to control rheumatoid arthritis, osteoarthritis and arthritis, low blood sugar and also being used for addison's disease and hence gives a number of medicinal uses including treatment of early addison's disease, cough suppression, gastric, duodenal ulcer, liver disease and dyspepsia also.…”

Section: Introductionmentioning

confidence: 99%

“…43 The roots contain different bioactive compounds e.g., various sugars (up to 18%), glycyrrhizin (16%), polyphenols, flavonoids, saponins, polysaccharides, sterols, amino acids, gums and essential oils. 44,45 Licorice contains a very important ingredient saponin known as glycyrrhizin (C 42 H 6 O 16 ) which is consist of two main parts named as glycyrrhetinic acid and glucuronic acid. 46 Glycyrrhizin is sometimes known for its cooling effect having licorice flavor.…”

Section: Introductionmentioning

confidence: 99%

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Preparation and characterization of electrospun nanofiber membrane from polyvinyl alcohol loaded with Glycyrrhiza glabra extract

Shahid

Khan²

2022

Polymers and Polymer Composites

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This study was designed to form an electrospun nanofiber membrane generated from different ratio of polyvinyl alcohol (PVA) and Glycyrrhiza glabra (licorice) extract. The electrospinning process was used to fabricate the nanofiber membrane using maximum amount of licorice extract solution. 90% licorice extract solution was successfully electrospun to fabricate nano membrane with 10% PVA solution. Antibacterial, cytotoxicity, scanning electron microscope (SEM) test were performed on resulted sample. The outstanding performance against Staphylococcus aureus ( S. aureus) by forming inhibition zone of 15 mm was observed. On the vero cell line, cell cytotoxicity was found, with only a few numbers of cells (less than 5%) surviving after exposure to the material. SEM investigation reveals fiber production with a diameter of (245.54 ± 55.19) nm on average. Moreover, Fourier transforms infrared spectroscopy (FT-IR) and moisture management test were performed. FT-IR spectra analysis confirmed the presence of licorice components in the membrane. Moisture analysis proved it as a better absorbing material. Since the fabricated membrane were proven to have bacteriostatic activity, it can be employed as wound healing.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Preparation and characterization of electrospun nanofiber membrane from polyvinyl alcohol loaded with Glycyrrhiza glabra extract

Shahid

Khan²

2022

Polymers and Polymer Composites

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“…RSM is based on the analysis of response as influenced by several factors, and its goal is to find the optimal condition of the response (Bezerra et al, 2008). Baite and Das (2018) optimised the extraction of GL from liquorice using a single screw extruder. Yang et al (2013) proposed an ionic liquid-based, ultrasonic-assisted method for extracting isoliquiritigenin, LQ, and GL from liquorice and optimised the technical parameters, including soaking time, solid-to-liquid ratio, ultrasonic power, and duration.…”

Section: Introductionmentioning

confidence: 99%

Comparison of extraction methods optimised by RSM for extraction of some bioactives from liquorice samples

ÖZCAN¹,

Özcan²,

Us³

et al. 2020

Turk J Agric For

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This study compared the extraction efficiency of 3 different techniques, ultrasound-assisted extraction (UAE), microwaveassisted extraction (MAE), and the classical extraction method, in obtaining some bioactive and allergen compounds, namely liquiritin (LQ), glycyrrhizin (GL), glycyrrhetinic acid (GA), and carbenoxolone (CBX), from liquorice samples of Glycyrrhiza glabra grown in Turkey. Extraction parameters for each technique were optimised by the response surface methodology-central composite design approach. Concentrations of LQ, GL, GA, and CBX, which were selected as the responses of selected independent variables, were determined by liquid chromatography-electrospray ionisation tandem mass spectrometry. One-way variance analysis was performed to evaluate the significance of the results. MAE was revealed as the most effective technique for extracting LQ (mean: 8.52 mg g −1 ), GL (mean: 76.65 mg g −1 ), and GA (mean: 1138.84 µg g −1 ) from liquorice, while the classical technique was the most effective for obtaining CBX (mean: 5.75 µg g −1 ).

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Green Approaches to Extraction of Natural Sweeteners: Recent Trends and Applications

Paulino

Araújo

Mano

et al. 2023

Sustainable Food Science - A Comprehensive Approach

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Extraction of glycyrrhizin from licorice using single screw extruder: Process kinetics and stimulus response modeling

Cited by 10 publications

References 24 publications

Preparation and characterization of electrospun nanofiber membrane from polyvinyl alcohol loaded with Glycyrrhiza glabra extract

Preparation and characterization of electrospun nanofiber membrane from polyvinyl alcohol loaded with Glycyrrhiza glabra extract

Comparison of extraction methods optimised by RSM for extraction of some bioactives from liquorice samples

Green Approaches to Extraction of Natural Sweeteners: Recent Trends and Applications

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