Extraction of Resveratrol from Melinjo (&lt;i&gt;Gnetum gnemon L&lt;/i&gt;.) Seeds Using Mixtures of Liquid Carbon Dioxide and Ethanol

Mishima, Kenji; Siregar, Yusraini Dian Inayati; Kawamura, Hirofumi; Kawakami, Ryo; Itô, Shota; Inoue, Yuuta; Hirota, Takako; Harada, Takunori; Kato, Takafumi; Misumi, Makoto; Suetsugu, Tadashi; Irie, Keiichi; Mishima, Kenichi; Mustofa, Salim; Hasanah, Fauziyah; Zaharo, Hilyatuz; Putri, Lily Surayya Eka; Salim, Agus

doi:10.15261/serdj.22.69

Cited by 3 publications

(2 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This result implies that lower or higher mole fractions of ethanol reduce the yield of -mangostin under our extraction conditions. This result is consistent with the results of our previous CO 2 extraction results for resveratrol [29]. …”

Section: Resultssupporting

confidence: 94%

Liquid Carbon Dioxide Extraction of Xanthones from the Pericarps of <i>Garcinia Mangostana</i> Linn. Enhanced by Ultrasonic Irradiation

Mishima

Kawamura

Itô

et al. 2015

SERDJ

Self Cite

View full text Add to dashboard Cite

The liquid carbon dioxide (CO 2 ) extraction of xanthones, such as α-mangostin from the pericarp of mangosteen (Garcinia mangostana Linn.), was enhanced using ultrasound at 5, 20 and 25 ºC. Mixtures of carbon dioxide and ethanol were used as solvents. The extraction pressure was from 8 to 14 MPa. To enhance the extraction yield, the solvent was irradiated with ultrasound. The yields of xanthones, such as α-mangostin, in the extraction were significantly improved without any change in the selectivity of the extract. We also qualitatively and quantitatively analyzed the xanthones in the extract using HPLC (high-performance liquid chromatography) as well as the extraction behavior. The effect of four operating parameters, temperature, pressure, ultrasound irradiation time and the composition of ethanol in the liquid CO 2 solution, on the extraction yield was investigated using single-factor experiments. The improved ratio in yields of each xanthone between the ultrasonic-enhanced case and unenhanced case was calculated. The yields of xanthones in the extract were significantly improved by adjusting the operating temperature, ultrasound irradiation time and the composition of ethanol in the liquid CO 2 solution, whereas no change in the selectivity of the extract was observed.

show abstract

Section: Resultssupporting

confidence: 94%

Liquid Carbon Dioxide Extraction of Xanthones from the Pericarps of <i>Garcinia Mangostana</i> Linn. Enhanced by Ultrasonic Irradiation

Mishima

Kawamura

Itô

et al. 2015

SERDJ

Self Cite

View full text Add to dashboard Cite

show abstract

“…The mobile phase solvent used was aqua pro injection:acetonitrile (75:25 v/v) at pH 3, regulated with the addition of 0.01% acetic acid. The detector used was a ultraviolet-visible detector and the column used was Inertsil 150 mm × 4.6 mm; 5 µm [17].…”

Section: Identification Of the Best Betaine-based Nades Componentmentioning

confidence: 99%

Ultrasonic-Assisted Extraction Using a Betaine-Based Natural Deep Eutectic Solvent for Resveratrol Extraction From Melinjo (Gnetum Gnemon) Seeds

2020

View full text Add to dashboard Cite

Objective: Melinjo (Gnetum gnemon L.) seeds are known to contain resveratrol, which are classified as a phenolic compound of the stilbenoid. Melinjoseeds have high water content, making them unstable to be stored for prolonged periods with open packaging at room temperature. The present studyaimed to explore the use of ultrasonic-assisted extraction with a betaine-based natural deep eutectic solvent (NADES) for resveratrol extraction fromirradiated melinjo seeds.Methods: The best betaine-based NADES component was identified among betaine-urea, betaine-lactic acid, and betaine-malic acid. Optimization ofextraction methods was performed using the best NADES and extraction variables such as time of extraction, water percentage, and sample: solventratio. The outcome of extraction was evaluated by measuring resveratrol content using high-performance liquid chromatography and the results wereanalyzed using response surface methodology.Results: The best betaine-based NADES was found to be betaine-lactic acid, yielding a resveratrol content of 0.3344 mg/g powder. The optimumextraction was achieved in 10 min with 60% water and a sample: solvent ratio of 1:10, yielding a resveratrol content of 0.227 mg/g powder.Conclusion: Betaine-based NADES can be purposed as an alternative solvent for resveratrol extraction from irradiated melinjo seeds.

show abstract

Ultrasonically enhanced extraction of luteolin and apigenin from the leaves of Perilla frutescens (L.) Britt. using liquid carbon dioxide and ethanol

Kawamura

Mishima

Sharmin

et al. 2016

Ultrasonics Sonochemistry

View full text Add to dashboard Cite

The present study reports on the ultrasonic enhancement of the liquid carbon dioxide (CO2) extraction of luteolin and apigenin from the leaves of Perilla frutescens (L.) Britt., to which ethanol is added as a cosolvent. The purpose of this research is also to investigate the effects of the particle size, temperature, pressure, irradiation power, irradiation time, and ethanol content in the liquid CO2 solution on the extraction yield using single-factor experiments. We qualitatively and quantitatively analyzed the yields in the extract using HPLC (high-performance liquid chromatography). The liquid CO2 mixed with ethanol was used at temperatures of 5, 20 and 25 °C with extraction pressures from 8 to 14 MPa. The yields of luteolin and apigenin in the extraction were clearly enhanced by the ultrasound irradiation, but the selectivity of the extract was not changed. The yields of luteolin and apigenin in the extract were also significantly improved by adjusting the operating temperature, the irradiation time, and the ethanol content in the liquid CO2 solution, but no change in the selectivity of the extract was observed.

show abstract

Extraction of Resveratrol from Melinjo (<i>Gnetum gnemon L</i>.) Seeds Using Mixtures of Liquid Carbon Dioxide and Ethanol

Cited by 3 publications

References 16 publications

Liquid Carbon Dioxide Extraction of Xanthones from the Pericarps of <i>Garcinia Mangostana</i> Linn. Enhanced by Ultrasonic Irradiation

Liquid Carbon Dioxide Extraction of Xanthones from the Pericarps of <i>Garcinia Mangostana</i> Linn. Enhanced by Ultrasonic Irradiation

Ultrasonic-Assisted Extraction Using a Betaine-Based Natural Deep Eutectic Solvent for Resveratrol Extraction From Melinjo (Gnetum Gnemon) Seeds

Ultrasonically enhanced extraction of luteolin and apigenin from the leaves of Perilla frutescens (L.) Britt. using liquid carbon dioxide and ethanol

Contact Info

Product

Resources

About