Extraction of tylosin from its aqueous solutions by Rotating Film-pertraction

Abstract

Removal of tylosin from its dilute aqueous solutions was studied applying the Rotating Filmpertraction technique. Non-toxic and practically water insoluble alcohols as n-octanol and n-decanol were used as intermediate, membrane liquid. A 0.001 mol/l solution of HCl was used as a stripping phase. Effects of temperature, feed phase pH-value and solute concentration on antibiotic distribution coef®cients were obtained for both systems. It was found that the ®rst two parameters have important effect, while the solute concentration in the studied range (0.02±0.1 g/l) did not modify these coef®cients. Results obtained show that the ®rst pertraction step ± solute extraction from the feed ± is a very fast process, while the second one ± the alcohol stripping ± is relatively slow, in particular when octanol was used as membrane phase. A mathematical model was proposed and used for evaluation of corresponding local mass transfer coef®cients. List of symbols a mass transfer area (m 2 ) K equilibrium constant (mol/m 3 ) k ®lm mass transfer coef®cient (m/s) m distribution coef®cient (±) j mass transfer¯uxes (mol/m 2 Á s) Ty tylosin in molecular form TyH tylosin in a protonised form t time (s) V phase volume (m 3 ) Superscript 0 initial value

Study of the influence of solute and carrier characteristics on facilitated pertraction mechanism in pseudosteady-state conditions

“…This phenomenon is described by the model given in Eq. (19). The correlations between the proposed model and the experimental data are indicated in Figs.…”

“…The liquid membranes can be obtained either by emulsification, but their stability is poor [1][2][3][4][10][11][12][13], by including the solvent in a hydrophobic porous polymer matrix [1,2,5,8,[14][15][16][17][18], or using pertraction equipments of special construction, which allow to separate and easily maintain the three phases without adding surfactants (free liquid membranes) [7,[19][20][21][22].…”

Extraction and preconcentration of tylosin from milk samples through functionalized TiO2nanoparticles reinforced with a hollow fiber membrane as a novel solid/liquid-phase microextraction technique

“…It has a broad spectrum of activity, being active against most Gram‐positive and Gram‐negative bacteria . In some countries, it is used for better food assimilation and for the acceleration of growth in poultry, although European Union (EU) legislation has forbidden this practice since January 1, 2006 . The widespread utilization of such antibiotics in animal husbandry can result in residues in several dairy products, such as milk, which is highly consumed all over the world .…”