Extradigestive manifestations of Helicobacter pylori gastric infection

Gasbarrini, Antonio; Franceschi, Francesco; Armuzzi, Alessandro; Ojetti, Veronica; Candelli, Marcello; Torre, E Sanz; Lorenzo, Antonino De; Anti, M.; Pretolani, S.; Gasbarrini, Giovanni

doi:10.1136/gut.45.2008.i9

Cited by 112 publications

(80 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The available data support an association between H. Pylori infection and ITP. 218 Studies have also shown that there is a significant increase in platelet count in patients with ITP after H. Pylori eradication. 220,222,223,224 Prevention of gastric cancer ACG recommends H. Pylori testing after endoscopic resection of early gastric cancer.…”

Section: Chronic Itpmentioning

confidence: 99%

Helicobacter Pylori Infection in Peptic Ulcer Disease

Tsang¹,

Shrestha²

2011

Peptic Ulcer Disease

View full text Add to dashboard Cite

Section: Chronic Itpmentioning

confidence: 99%

Helicobacter Pylori Infection in Peptic Ulcer Disease

Tsang¹,

Shrestha²

2011

Peptic Ulcer Disease

View full text Add to dashboard Cite

“…Since the discovery in 1983 that the stomach could be colonized by bacteria [3], sufficient evidence has accumulated implicating H. pylori as a pathogen intimately related to benign stomach diseases, such us chronic gastritis and duodenal and gastric peptic ulcers [3], and malignant diseases, for example gastric cancer [4] and gastric MALT lymphoma [5]. Furthermore, during the last three decades following the discovery [3], approximately 50 extragastric diseases have been reported in medical specialties such as cardiology, dermatology, endocrinology, obstetrics and gynecology, pneumology, neurology, odontology, ophthalmology, otorhinolaryngology, pediatrics, and hematology [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20], the last of which is the subject of this review.…”

Section: Introductionmentioning

confidence: 99%

Helicobacter pylori and Hematologic Diseases

Campuzano-Maya¹

2016

Extradigestive Manifestations of Helicobacter Pylori Infection - An Overview

View full text Add to dashboard Cite

Helicobacter pylori infection is the most common infection of the human species, with developing countries displaying a marked disadvantage in contrast to developing countries. While H. pylori infection is asymptomatic in most infected individuals, it is intimately related to malignant diseases of the stomach, such as gastric cancer and gastric MALT lymphoma, as well as benign diseases, for example chronic gastritis and duodenal and gastric peptic ulcers. Since the discovery that gastric mucosa could be colonized by bacteria, evidence of greater than 50 extragastric manifestations has been reported, linking H. pylori infection and the development of diseases associated with cardiology, dermatology, endocrinology, obstetrics and gynecology, hematology, pneumology, neurology, odontology, ophthalmology, otorhinolaryngology, and pediatrics. This chapter presents the extragastric manifestations of H. pylori infection expressed through hematologic diseases; particularly those included in the international consensus, and discusses guidelines for the management of H. pylori infection, such as iron deficiency, vitamin B 12 (cobalamin) deficiency, and immune thrombocytopenia. Other manifestations reviewed include immune neutropenia, antiphospholipid syndrome, and plasma cell dyscrasias, such us monoclonal gammopathy of undetermined significance, multiple myeloma, and Henoch-Schönlein purpura.

show abstract

“…In the last years, H. pylori infection has been associated with some extradigestive pathologies, and expecially with organic and functional vascular disorders [9][10][11][12][13][14][15][16]. In particular, our group [11] recently reported a high prevalence of H. pylori infection, with particular regard to cytotoxic strains, in patients with migraine.…”

Section: Introductionmentioning

confidence: 99%

Beneficial effects of Helicobacter pylori eradication on migraine: a 12-month follow-up study

Gabrielli¹,

Franceschi²,

Fiore

et al. 2001

J Headache Pain

View full text Add to dashboard Cite

Helicobacter pylori (H. pylori) has been recently associated with some organic and functional vascular disorders. In particular, our group found a high prevalence of H. pylori in patients affected by migraine and a significant improvement of migraine symptoms after eradication of the bacterium, during a follow-up period of 6 months. However, seasonal variations may affect clinical manifestations of migraine, thus influencing our previous results. The present study evaluated the effect of H. pylori eradication during a 1-year follow-up period in a population of 148 consecutively enrolled migraine patients. H. pylori infection was assessed by 13 C-urea breath test. Infected subjects underwent specific antibiotic treatment in order to eradicate the bacterium. Frequency, intensity and duration of attacks of migraine were assessed during a 1-year follow-up period. 42% of the patients showed H. pylori infection. 82% resulted eradicated. Interestingly, 28% of the patients reported a disappearance of migraine during the follow-up period. Moreover, a significant decrease of intensity, frequency and duration of the migraine attacks evaluated 2, 4, 6 and 12 months from H. pylori eradication was observed in the remaining patients. The beneficial effects of H. pylori eradication on migraine seem to be confirmed by this prolonged 1-year follow-up study.

show abstract

Extradigestive manifestations of Helicobacter pylori gastric infection

Cited by 112 publications

References 41 publications

Helicobacter Pylori Infection in Peptic Ulcer Disease

Helicobacter Pylori Infection in Peptic Ulcer Disease

Helicobacter pylori and Hematologic Diseases

Beneficial effects of Helicobacter pylori eradication on migraine: a 12-month follow-up study

Contact Info

Product

Resources

About