Extragastrointestinal Stromal Tumour of The Abdominal Wall - A Case Report

Kumar, Aman; Padmini, R; Veena, G; Murugesan, Nivetha

doi:10.7860/jcdr/2013/7863.3812

Cited by 7 publications

(12 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In recent years, a handful of case reports and case series have described GIST-associated NICTH [4, 9, 11]. GIST tumors arise from the gut wall.…”

Section: Discussionmentioning

confidence: 99%

“…In rare instances, they arise outside the GI tract in the omentum, mesentery, and retroperitoneum and are referred to as EGISTs. EGISTs share the same histological and immunotypic features and biological behavior as GISTs [4, 14]. The diagnosis of GIST/EGIST tumors relies on CD117 (c-KIT) positivity on immunohistochemical staining, which remains a highly sensitive and specific marker.…”

Section: Discussionmentioning

confidence: 99%

“…These tumors express the phenotype of the Interstitial Cells of Cajal or related stem cell-like precursors and are associated with somatic mutations of the tyrosine kinase receptors c-kit (CD117) and platelet-derived growth factor-α (PDGFR-α) [4–6]. Over the last decade, a handful of case reports have described an association between GIST and NICTH [5].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A case of extragastrointestinal stromal tumor complicated by severe hypoglycemia: a unique presentation of a rare tumor

2016

View full text Add to dashboard Cite

BackgroundNon-Islet Cell Tumor Hypoglycemia (NICTH) is a rare paraneoplastic cause of hypoglycemia arising from excess tumor production of insulin-like growth factor. The objective of this report is to describe an unusual case of Extragastrointestinal Stromal Tumor (EGIST) associated NICTH.Case presentationA 64 year-old African female was brought to the emergency room with a 1-month history of recurrent syncope, weight loss, and abdominal bloating. Serum blood glucose was discovered to 39 mg/dL, when insulin, proinsulin, and C-peptide were suppressed. Computed tomography scan revealed a diffuse extraintestinal metastatic disease process, and a biopsy confirmed the diagnosis of an Extragastrointestinal Stromal Tumor (EGIST). IGF-I and II levels were 27 ng/ml and 262 ng/ml respectively, and the ratio of IGF-II to IGF-I was calculated as 9.7:1, suggestive of IGF-II-mediated NICTH. Acutely, the patient’s hypoglycemia resolved with dextrose and glucagon infusion. Long-term euglycemia was achieved with prednisone and imatinib therapy.ConclusionsNICTH should be considered when hypoglycemia occurs in the setting of low serum insulin levels. Whereas definitive treatment of EGIST involves surgical resection, immunotherapy with tyrosine kinase inhibitors and corticosteroids have been shown to alleviate hypoglycemia in cases where surgery is delayed or not feasible.

show abstract

“…In recent years, a handful of case reports and case series have described GIST-associated NICTH [4, 9, 11]. GIST tumors arise from the gut wall.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A case of extragastrointestinal stromal tumor complicated by severe hypoglycemia: a unique presentation of a rare tumor

2016

View full text Add to dashboard Cite

show abstract

“…4C y 4D), sarcomas, GIST, melanomas y neoplasias hemolinfopoyéticas pueden ser la causa de metás-tasis o implantes en la pared abdominal [50][51][52][53][54][55][56][57][58][59][60][61][62] . Dentro del grupo de los carcinomas, las metástasis cutáneas, subcutáneas o en tejidos blandos de pared han sido reportadas en pacientes con antecedentes de cáncer de mama, tracto genitourinario, colon, estómago, riñón, carcinoma hepatocelular, vesícula biliar, cáncer ginecológico, esófago, tiroides y pulmón 5,12,13,[50][51][52][53][54][55][56] .…”

Section: Tumores Metastásicos En Pared Abdominalunclassified

Lesiones ocupantes de espacio en pared abdominal (no herniaria). La visión del patólogo

Machado

Cruz

Carbonell

2015

Revista Hispanoamericana de Hernia

View full text Add to dashboard Cite

“…Aggressive fibromatosis is an often-used term to emphasize its frequently aggressive behavior. DT accounts for 0.03% of all neoplasms and 3% of soft tissue tumors, with a reported incidence of [2][3][4] They usually arise in the mesentery, omentum or retroperitoneum, while the abdominal wall is very rare 3 . DT tends to occur in young women.…”

Section: Introductionmentioning

confidence: 99%

Uncommon abdominal wall mass in a young boy: Desmoid tumor

Cankorkmaz¹,

Atalar²,

Eğilmez³

2018

Cumhuriyet Medical Journal

View full text Add to dashboard Cite

SUMMARYFibromatosis that arises in musculoaponeurotic structures of the abdominal wall is called abdominal fibromatosis, abdominal desmoid tumor (DT), or aggressive fibromatosis. Fibromatoses occur at various anatomic locations with different clinical features. Abdominal fibromatosis tends to occur in young women. Conversely, in children is an extremely rare condition. Herein, we report the case of a 15-year-old boy with desmoid tumor. He was referred to our department because of a growing painful mass in the right lumbar area. There was no history of known trauma or surgery prior to the time. He was active wrestler. Ultrasonography demonstrated a solid and relatively well-circumscribed mass. Magnetic resonance imaging demonstrated a well-defined tumor originating from the abdominal transversal muscle and internal abdominal oblique muscle fascia. The mass was total excised. The histological diagnosis was desmoid tumor. In conclusion, in child patients presenting a painful tumors of the lower abdominal wall as well as DT should be considered. Recurrent sports trauma during wrestling can be a factor for this tumor, in our case. Keywords: Desmoid tumor, abdominal wall, child ÖZET Karın duvarının kas-aponörotik yapılarından köken alan fibromatozislere abdominal fibromatozis, abdominal desmoid tümör (DT), ya da agressif fibromatozis adı verilir. Fibromatozisler farklı anatomik lokalizasyonlarda farklı klinik özelliklerde olabilirler. DT genç kadınlarda daha sıktır. Çocuklarda ise oldukça ender bir durumdur. Bu yazıda 15 yaşında desmoid tümörlü bir erkek olgu sunuldu. Hasta hastanemize sağ lumbal bölgede büyüyen ağrılı bir kitlenin farkedilmesi üzerine sevk edilmişti. Hastanın öncesinde bilinen bir travma ya da operasyon öyküsü yoktu. Aktif olarak güreş yapmaktaydı. Ultrasonografisinde solid ve göreceli olarak iyi sınırlı kitle saptandı. Manyetik rezonans görüntülemede iyi sınırlı, abdominal transversalis kası ile internal abdominal oblique kasının fasyasından kaynaklanan kitle saptandı. Kitle genel anestezi altında total olarak eksize edildi. Kitlenin histopatolojik incelemesinde desmoid tümör tanısı konuldu. Sonuç olarak lateral abdominal bölgede ağrılı kitle yakınmasıyla başvuran çocuklarda DT de ayırıcı tanıda dikkate alınması gereken bir patolojidir. Olgumuzda güreş sırasındaki yineleyen spor travması bu tümörün gelişiminde bir faktör olabilir diye düşünmekteyiz.

show abstract

Extragastrointestinal Stromal Tumour of The Abdominal Wall - A Case Report

Cited by 7 publications

References 9 publications

A case of extragastrointestinal stromal tumor complicated by severe hypoglycemia: a unique presentation of a rare tumor

A case of extragastrointestinal stromal tumor complicated by severe hypoglycemia: a unique presentation of a rare tumor

Lesiones ocupantes de espacio en pared abdominal (no herniaria). La visión del patólogo

Uncommon abdominal wall mass in a young boy: Desmoid tumor

Contact Info

Product

Resources

About