Extragonadal choriocarcinoma involving the kidney

Appu, Sree; O’Connell, Helen; Cleeve, Laurence K.; Fox, Richard M.

doi:10.1046/j.1440-1622.2001.02115.x

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…We therefore again decided to switch therapy to actinomycin D, cyclophosphamide and etoposide followed by cisplatin, vincristine, methotrexate, bleomycin (POMB/ACE) given a prior report of efficacy with this regimen in male upper urinary tract choriocarcinoma. 6 Accordingly, on 11/04/13 the patient was started on actinomycin D 0.5 mg daily on days 3–5, cyclophosphamide 500 mg/m 2 IV on day 5, and etoposide 100 mg/m 2 on days 1–5 (ACE), with pegfilgrastim support. He also received another dose of testosterone supplementation to minimize any chance of spurious β-hCG readings.…”

Section: Case Reportmentioning

confidence: 99%

Prolonged Remission of Upper Urinary Tract Urothelial Carcinoma With Prominent Choriocarcinomatous Differentiation: A Case Report

Msaouel

Zhang

2017

Clinical Genitourinary Cancer

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Section: Case Reportmentioning

confidence: 99%

Prolonged Remission of Upper Urinary Tract Urothelial Carcinoma With Prominent Choriocarcinomatous Differentiation: A Case Report

Msaouel

Zhang

2017

Clinical Genitourinary Cancer

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“…Most cases arise in the midline structures with male predominance, and often coexist with other germ‐cell tumor components 1,2 . However, non‐gestational choriocarcinoma infrequently involves non‐midline lesions with no other germ‐cell tumor components 3–46 . Primary pulmonary choriocarcinoma is an extremely rare neoplasm representing such tumors 17–39 .…”

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confidence: 99%

Primary pulmonary choriocarcinoma combined with adenocarcinoma

Yamamoto¹,

Tanaka

Takeo³

et al. 2006

Pathology International

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An extremely rare autopsy case of primary pulmonary choriocarcinoma combined with adenocarcinomatous components in a 77-year-old Japanese man is described. The patient died of rapidly progressive respiratory dysfunction without ante-mortem diagnosis. Autopsy revealed necro-hemorrhagic areas of the primary lung tumor with a typical biphasic pattern of choriocarcinoma. Topographical analysis suggested that moderately to poorly differentiated adenocarcinoma components partially surrounded the choriocarcinomatous components. Moreover, dedifferentiated carcinomatous components were scattered next to both adenocarcinomatous and choriocarcinomatous areas, and a few cells of the dedifferentiated carcinomatous components had a similar immunoreaction to conventional adenocarcinomatous or choriocarcinomatous components, such as surfactant apoprotein A, placental alkaline phosphatase or beta-human chorionic gonadotropin. Additionally, epithelial membrane antigen-positive cytotrophoblastic cells were rarely found in choriocarcinomatous areas. The present case suggests that primary lung choriocarcinoma can occur closely related to conventional pulmonary adenocarcinoma, although collision tumor was not completely ruled out.

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Extragonadal choriocarcinoma involving the kidney

Cited by 2 publications

References 9 publications

Prolonged Remission of Upper Urinary Tract Urothelial Carcinoma With Prominent Choriocarcinomatous Differentiation: A Case Report

Prolonged Remission of Upper Urinary Tract Urothelial Carcinoma With Prominent Choriocarcinomatous Differentiation: A Case Report

Primary pulmonary choriocarcinoma combined with adenocarcinoma

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