Extramedullary Plasmacytoma of the Pancreas: A Rare Entity

Smith, Anita; Hal, Hassan; Frauenhoffer, Elizabeth E.

doi:10.1155/2012/798264

Cited by 11 publications

(12 citation statements)

References 9 publications

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“…Radiotherapy is considered a plausible option for treating non-head-and-neck EMP as it achieves symptomatic control and is likely to be less toxic compared with surgery and chemotherapy [ 6 ]. Evidence of this fact is supported by individual cases in the literature although there are no clinical studies categorically confirming it [ 1 , 2 , 3 , 4 , 5 ]. In some cases, radiotherapy is given after the failure of previous treatments, but in those cases, cumulative toxicity may be expected.…”

Section: Discussionmentioning

confidence: 99%

“…Solitary EMPs of the retroperitoneum are rare with few reports in the literature [ 2 ]. Plasma cell tumors tend to be radio- and chemosensitive; therefore, the treatment of choice for EMPs can either be surgery, chemotherapy or radiotherapy [ 3 ]. The best choice for treatment is not evident [ 2 ], but most cases are localized, and some studies have shown that radical radiotherapy offers potential local control and organ preservation associated with low toxicity [ 4 , 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

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A Case of Post-Radiotherapy Gastritis: Radiation Does Not Explain Everything

Abrunhosa-Branquinho¹,

et al. 2014

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Hemorrhagic gastritis is a possible late toxicity outcome after radical radiotherapy but it is nowadays a very rare condition and most likely depends on other clinical factors. We report the case of a 77-year-old woman with a symptomatic solitary extramedullary intra-abdominal plasmacytoma and multiple gastric comorbidities, treated with external beam radiotherapy. Despite the good response to radiotherapy, the patient experienced multiple gastric bleeding a few months later, with the need of multiple treatments for its control. In this paper we will discuss in detail all aspects related to the different causes of hemorrhagic gastritis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Case of Post-Radiotherapy Gastritis: Radiation Does Not Explain Everything

Abrunhosa-Branquinho¹,

et al. 2014

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“…A number of studies investigating the CT findings of EMPs in other organs were identified during the literature search for the present study. One study, which examined a case of pancreatic EMP, demonstrated a large homogeneously-enhancing mass in the region of the pancreatic head ( 9 ). A second study revealed a well-demarcated, minimally homogeneously-enhancing, 1.5×1.0×1.2-cm mass in the left arytenoid region of the larynx ( 10 ).…”

Section: Discussionmentioning

confidence: 99%

Computed tomography findings of a solitary extramedullary plasmacytoma of the spleen: A case report and literature review

et al. 2014

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Solitary extramedullary plasmacytoma (EMP) of the spleen is a rare condition. The present study describes the case of a 23-year-old female with an extremely rare solitary EMP of the spleen. Upon examination, the tumor demonstrated unusual and notable multiple-phase spiral computed tomography (CT) findings. The lesion was a solitary, well-defined mass, with areas of variable splenic necrosis and cystic degeneration. Contrast-enhanced CT revealed progressive enhancement of the lesion in the cystic wall, internal septa and solid portion, a finding that has not previously been described. The patient underwent a splenectomy and recovered without complications. No evidence of tumor recurrence has occurred during the past two years of follow-up. To the best of our knowledge, this is the first study to examine the CT findings of a solitary EMP of the spleen. The study aimed to investigate the imaging features of solitary EMP, in particular the multiple-phase spiral CT findings, and raise awareness of the disease to reduce misdiagnoses.

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“…The pancreas is rarely infiltrated by plasma cells as an EMP, and obstructive jaundice is also rarely diagnosed as a result of plasma cell neoplasms (2). Only 25 cases have been reported in the English literature to date (3). We reported a case of pancreatic plasmacytoma presenting with obstructive jaundice.…”

Section: Introductionmentioning

confidence: 92%

Biliary Obstruction Secondary to an Extramedullary Plasmacytoma of the Pancreas

Coskun¹,

Kaynar²,

Yagbasan³

2015

Erciyes Med J

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Extramedullary plasmacytoma (EMP) is an uncommon neoplastic disorder arising from B-cell lymphocytes and comprises 3% of the plasma cell neoplasms. Ninety percent of the cases are encountered in the head and neck regions. The involvement of the pancreas is rare and generally develops as secondary multiple myeloma (MM). To date, four cases of EMP of the pancreas, which developed as secondary solitary bone plasmacytoma, have been reported in the literature. We decided to present this rare case, which was diagnosed and treated at our clinic.

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Extramedullary Plasmacytoma of the Pancreas: A Rare Entity

Abstract: Extramedullary plasmacytomas are plasma cell neoplasms in organs other than the bone marrow. Most are found in the upper respiratory tract. Involvement of the pancreas is rare. We report a case of pancreatic plasmacytoma in association with advanced multiple myeloma.

Cited by 11 publications

References 9 publications

A Case of Post-Radiotherapy Gastritis: Radiation Does Not Explain Everything

A Case of Post-Radiotherapy Gastritis: Radiation Does Not Explain Everything

Computed tomography findings of a solitary extramedullary plasmacytoma of the spleen: A case report and literature review

Biliary Obstruction Secondary to an Extramedullary Plasmacytoma of the Pancreas

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