Extranodal Marginal Zone B-cell Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of Cecum Presenting as Bright Red Bleed per Rectum—A Case Report with Review of Literature

A 62-year-old man with a chief complaint of dysphagia visited our hospital. Enhanced computed tomography showed the tumor near the duodenal wall and lymphadenopathy in the left supraclavicular fossa and para-aortic lymph node. Upper gastrointestinal endoscopy showed an ulcer accompanied with a fistula in the anterior wall of duodenal bulb, suggesting that the tumor penetrated into duodenal wall. Biopsy from the lymph node in the left supraclavicular fossa indicated diffuse large B-cell lymphoma. Although chemotherapy was planned, massive arterial bleeding occurred from the part of duodenal penetration. Endoscopic hemostasis was unsuccessfully performed. Therefore, we performed transcathether arterial embolization for hemostasis. After the procedure, the patient received six cycles of chemotherapy, and he achieved complete response. He has been alive 5 years without recurrence. There were many cases of gastrointestinal bleeding from primary gastrointestinal lymphomas, while there were few cases with nodal involvement by malignant lymphoma resulting in bleeding from gastrointestinal tract. We herein report a case of duodenal bleeding by nodal involvement of diffuse large B-cell lymphoma with review of literature.

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A case of nodal malignant lymphoma presenting with arterial bleeding related to its duodenal penetration

Miyake

Iida

Masaki

et al. 2018

Clin J Gastroenterol

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Extranodal Marginal Zone B-cell Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of Cecum Presenting as Bright Red Bleed per Rectum—A Case Report with Review of Literature

Abstract: The diagnosis may be challenging, but a solitary extranodal plasmacytoma and multiple myeloma must be excluded in all such cases.

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A case of nodal malignant lymphoma presenting with arterial bleeding related to its duodenal penetration

A case of nodal malignant lymphoma presenting with arterial bleeding related to its duodenal penetration

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