Extraskeletal Ewing's Sarcoma of parapharyngeal space

Chaudhary, Neena; Dk, Gupta; Natesh, V.; Singh, Seema

doi:10.1016/j.pedex.2009.08.004

Cited by 6 publications

(3 citation statements)

References 16 publications

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“…The relationship between EES and pPNET represents one of the most fascinating controversies in pathology. Both EES and pPNET show varying degree of neuroectodermal differentiation [11]. The term EES has been used for those tumors that lack neuroectodermal differentiation by light microscopy, immunohistochemistry and electron microscopy [18].…”

Section: Discussionmentioning

confidence: 99%

“…EES arising in head and neck is extremely rare and only some cases have been reported in the orbit, scalp, face, nasal cavity, paranasal sinus, nasopharynx, parapharyngeal space, larynx, hard palate, submandibular gland, parotid gland, thyroid gland, and soft tissue of the neck [4][5][6][7][8][9][10][11][12][13][14][15][16][17]. However, no case originating from the pterygomandibular space has been reported to date.…”

Section: Discussionmentioning

confidence: 99%

“…Although it has been reported in the orbit [4], scalp [5], face [6], nasal cavity [7], paranasal sinus [8], nasopharynx [9], parapharyngeal space [10,11], larynx [12], hard palate [13], submandibular gland [14], parotid gland [15], thyroid gland [16] and soft tissue of the neck [17], to our knowledge, there has been no documented case regarding involvement of the pterygomandibular space by EES. This article reports a rare case of EES originating from the pterygomandibular space with the submandibular space, mouth floor extension and describes the clinical, radiological, histopathological and immunohistochemical features.…”

Section: Introductionmentioning

confidence: 98%

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Extraosseous Ewing's sarcoma arising from the pterygomandibular space

Li¹,

Huang²,

Chen³

et al. 2011

OJST

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Extraosseous Ewing's sarcoma (EES) arising in head and neck is extremely rare. We report on a rare case of EES originating from the pterygomandibular space. A 15-year-old boy was seen with a rapidly growing mass in the right upper neck, difficulty in opening mouth, dysphagia, numbness in the right lower lip and buccal skin. Clinical and radiological examinations indicated that a soft tissue mass originated from the pterygomandibular space with the submandibular space and mouth floor extension. Histological and immunohistochemical evaluations of the biopsy specimen revealed poorly differentiated small blue round cells with positive stains for CD99 and neuron-specific enolase. According to the clinical manifestation, CT and MRI findings, histological pattern and the results of the immunohistochemical studies, the final diagnosis was EES. Our patient was treated with chemotherapy and radiotherapy. The lesion recurred locally after 10 months and he died of multiple distant metastases 22 months later. Early and confident diagnosis coupled with combined surgical excision and modern chemotherapy/radiotherapy appears to be the most effective treatment plan.

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Section: Discussionmentioning

confidence: 99%