The term granulomatous peritonitis encompasses a wide range of unusual forms of inflammation of the peritoneum that have simmilar clinical, pathological, and imaging features. Infectious agents such as mycobacteria, fungi, foreign substances such as talc and barium; meconium; intestinal contents; contents of a ruptured ovarian cyst; gall stones; nematode eggs or unknown agents can cause granulomatous peritonitis. Most of the listed nosological forms of peritoneal lesions are not described, whereas vessels, lung tissue, intestines, kidneys, liver, lymph nodes are often the target organs. So far there are very fewpapers in the medical literature covering questions such as the spreading of granulomatous peritonitis, methods of their diagnosis, differential diagnosis and treatment. This review is an attempt to fill this gap.