Fabrication and application of copper metal–organic frameworks as nanocarriers for pH-responsive anticancer drug delivery

Synthesis and investigation on microstructural, mechanical features of mesoporous hardystonite/reduced graphene oxide nanocomposite for medical applications

“…Moreover, from BJH method the single point adsorption total volume (V P ) at P/P 0 = 0.98 for the HT/GO 1% and the HT/RGO 1% materials were 0.0045 and 0.0037 cm 3 g −1 , respectively. These decreases of pore volume and pore diameter in HT/RGO could be due to the generation of the amount of defects in the mesoporous structure of HT composite after being scaffolded and hydrothermal treatment ( Zhang, 2013 ; Karamian and Gheisari, 2015 ; Gharehdaghi et al, 2022 ).…”

Combining Copper and Zinc into a Biosensor for Anti-Chemoresistance and Achieving Osteosarcoma Therapeutic Efficacy

“…The appropriate combination of them contributed higher efficiencies, such as 80 wt% ibuprofen and 83.5% metformin loadings and a 98% tetracycline clearance rate as shown in Table 1. Cu3-(BTC)2 and Cu-TCPP may include iron oxide nanoparticles and grapheme oxide for magnetic and photo biosensors, respectively, to trigger doxorubicin release [131]. The electrical biosensor combined with either the magnetic or photo biosensor contributed higher efficiencies, such as 40.5 wt % or 45.7 wt % adsorptions and 85.5% or 98.9% release, respectively, as shown in Table 1.…”

Metalloporphyrin Metal–Organic Frameworks: Eminent Synthetic Strategies and Recent Practical Exploitations

“…Metal ions’ sensing and realization abilities can be achieved via the modulation of their optical and electronic nature derived from the coordination of the metal site and their axial connection to molecules. Last but not least, their similarity to several molecules operating in the core site of the vital proteins in humans, has led to them being frequently used for plenty of biological utilizations such as biocompatibility, imitating functions in numerous biological systems [ 9 , 23 , 46 ], effectual removal and longer resistance against tumors, as they have less side effects, and they have also been largely employed as photosensitizers for photodynamic therapy (PDT) [ 25 , 26 ]. Concomitantly, their fluorescence properties suggest that porphyrin-based photosensitizers are beneficial fluorescence imaging-guided therapy systems for tumor or a multitude of diseases [ 57 , 58 ].…”

“…The recently emerged porous materials, metal–organic frameworks (MOFs)—typically formed from metal ions/clusters bridged by multidentate ligands in an extended framework—have provided solutions to tackle challenges in areas such as catalysis [ 1 , 2 , 3 ], gas storge/separation [ 4 , 5 ], biomimetic applications [ 6 , 7 , 8 ], drug delivery [ 9 , 10 , 11 ], electrochemical applications [ 12 , 13 ] and biomedical chemistry [ 14 , 15 ]. Moreover, the structures can be tuned by replacing or incorporating specific linkers or suitable unsaturated metal ions, in addition to adjusting the pore size and/or geometry which substantially influence their catalytic behaviors toward many substances participating in the reaction [ 16 , 17 ].…”