Fabrication and Characterization of Noble Crystalline Silver Nanoparticles from <i>Ceropegia bulbosa</i> Roxb Root Tuber Extract for Antibacterial, Larvicidal and Histopathology Applications

Vetrivel, Cittrarasu; Balasubramanian, Balamuralikrishnan; Durairaj, Kaliannan; Park, Sungkwon; Velmurugan, Palanivel; Ragavendran, Chinnasamy; Sigamani, Santhosh; Maruthupandian, A.

doi:10.1166/nnl.2019.2845

Cited by 14 publications

(9 citation statements)

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“… Vetrivel et al (2019) synthesized crystalline AgNPs through green synthesis using Ceropegia bulbosa Roxb root tuber extract and observed XRD diffraction peaks at the 111, 200, 220, and 311 planes, which correspond to the AgNPs. Synthesized AgNPs were also confirmed for their antibacterial and larvicidal activity.…”

Section: Resultsmentioning

confidence: 99%

Green synthesis of silver nanoparticles using aqueous rhizome extract of Zingiber officinale and Curcuma longa: In-vitro anti-cancer potential on human colon carcinoma HT-29 cells

Venkatadri

Shanparvish

Rameshkumar

et al. 2020

Saudi Journal of Biological Sciences

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This study was aimed to analyze the anti-cancer activity of silver nanoparticles (AgNPs) synthesized using aqueous plant extracts from the rhizome of Curcuma longa and Zingiber officinale. Synergistic aqueous extract of rhizome of C. longa and Z. officinale was used to green synthesis of AgNPs. Characterization of AgNPs was performed using UV–visible spectroscopy, FTIR, X-ray diffraction, TEM, and SEM analyses. Anti-cancer activity of AgNPs against human colon carcinoma (HT-29) cells was tested using MTT assay. UV–Visible spectroscopy analysis indicated the surface plasmon resonance (SPR) sharp peak at 350–430 nm wavelength that corresponds to the production of AgNPs. FTIR analysis reveals that existence of carboxyl (—C O) and amine (N—H) functional groups in the AgNPs. The X-ray diffraction analysis confirms four spectral peaks at 111, 200, 220, and 311. SEM analysis showed that AgNPs are in a spherical shape with a size of 42–61 nm and TEM analysis showed particle size are ranged between 20–51 nm. Anti-cancer study reveals that AgNPs had shown cytotoxicity against HT-29 cells at the concentrations ranged from 25 to 500 μg/mL and IC 50 at 150.8 µg/mL. This study concludes that AgNPs synthesized using rhizome of Z. officinale and C. longa possesses potential anti-cancer activity.

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Section: Resultsmentioning

confidence: 99%

Green synthesis of silver nanoparticles using aqueous rhizome extract of Zingiber officinale and Curcuma longa: In-vitro anti-cancer potential on human colon carcinoma HT-29 cells

Venkatadri

Shanparvish

Rameshkumar

et al. 2020

Saudi Journal of Biological Sciences

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“…BS1/SRC/5/23/2017/Tech/1952) at Botanical Survey of India, Coimbatore. Aqueous extraction from the plants were carried out as per previous report 7 .…”

Section: Methodsmentioning

confidence: 99%

“…Presently, mosquito's act a massive spreader of urban diseases in rural India. To deal with this cataclysm researchers recommend advanced green nanotechnology technics to acquire solutions for vector disease 7 . Selenium is one of the critical trace elements required for normal functioning in the living cells of mammals and higher animals [8][9][10] .…”

mentioning

confidence: 99%

Green synthesis of selenium nanoparticles mediated from Ceropegia bulbosa Roxb extract and its cytotoxicity, antimicrobial, mosquitocidal and photocatalytic activities

Vetrivel

Durairaj

Kalaimurugan

et al. 2021

Sci Rep

181

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The present study is to design an eco-friendly mode to rapidly synthesize selenium nanoparticles (SeNPs) through Ceropegia bulbosa tuber’s aqueous extracts and confirming SeNPs synthesis by UV–Vis spectroscopy, FT-IR, XRD, FE-SEM-EDS mapping, HR-TEM, DLS and zeta potential analysis. In addition, to assess the anti-cancer efficacy of the SeNPs against the cultured MDA-MB-231, as studies have shown SeNPs biosynthesis downregulates the cancer cells when compared to normal HBL100 cell lines. The study observed the IC50 value of SeNPs against MDA-MB-231 cells was 34 µg/mL for 48 h. Furthermore, the SeNPs promotes growth inhibitory effects of certain clinical pathogens such as Bacillus subtilis and Escherichia coli. Apart, from this the SeNPs has shown larvicidal activity after 24 h exposure in Aedes albopitus mosquito’s larvae with a maximum of 250 g/mL mortality concentration. This is confirmed by the histopathology results taken at the 4th larval stage. The histopathological studies revealed intense deterioration in the hindgut, epithelial cells, mid gut and cortex region of the larvae. Finally, tried to investigate the photocatalytic activity of SeNPs against the toxic dye, methylene blue using halogen lamp and obtained 96% degradation results. Withal computational study SeNPs was shown to exhibit consistent stability towards breast cancer protein BRCA2. Overall, our findings suggest SeNPs as a potent disruptive agent for MDA-MB-231 cells, few pathogens, mosquito larvae and boosts the photocatalytic dye degradation.

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“…extractmediated AgNPs reported a maximum larvicidal activity against C. quinquefasciatus mosquito vector with LC 50 and LC 90 values of 0.64 and 8.88 ppm, respectively. Vetrivel et al (2019) also reported that the AgNPs prepared by Ceropegia bulbosa Roxb. leaf extract exhibited a potential insecticidal activity against A. albopictus having LC 50 and LC 90 values of 0.50 and 1.24 ppm, respectively.…”

Section: Bioassay Studies Of Silver Nanoparticles Against the Larvae mentioning

confidence: 91%

“…Recently, plant-derived silver nanoparticles have also emerged as an alternative tool and received extraordinary attention as potent larvicidal agents in recent past (Santhosh et al 2015). Silver nanoparticles have been synthesized using Annona reticulata Linnaeus (Parthiban et al 2019), Chasmanthera dependens Hochst (Aina et al 2019), Ceropegia bulbosa Roxburgh (Vetrivel et al 2019), Piper longum Linnaeus (Yadav et al 2019), Cullen corylifolium Linnaeus (Saini et al 2019), Curcuma zedoaria Roscoe (Sutthanont et al 2019), Naringi crenulata Roxburgh (Pratheeba et al 2019), and Avicennia marina Forsskål (Barnawi et al 2019); they exhibit tremendous larvicidal potential against various mosquito vectors. Herbal silver nanoparticles have several advantages over the chemically synthesized silver nanoparticles like eco-friendly, cost-effective, single-step synthesis, and an easy control of crystal growth, and also, they are non-toxic and safe to handle (Iravani 2011; Salam et al 2012;Shah et al 2016;Benelli 2016a;Das et al 2017;Murugan et al 2017).…”

Section: Introductionmentioning

confidence: 99%

Biocontrol of mosquito vectors through herbal-derived silver nanoparticles: prospects and challenges

Kumar

Singh

et al. 2020

Environ Sci Pollut Res

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Mosquitoes spread several life-threatening diseases such as malaria, filaria, dengue, Japanese encephalitis, West Nile fever, chikungunya, and yellow fever and are associated with millions of deaths every year across the world. However, insecticides of synthetic origin are conventionally used for controlling various vector-borne diseases but they have various associated drawbacks like impact on non-targeted species, negative effects on the environment, and development of resistance in vector species by alteration of the target site. Plant extracts, phytochemicals, and their nanoformulations can serve as ovipositional attractants, insect growth regulators, larvicides, and repellents with least effects on the environment. Such plant-derived products exhibit broad-spectrum resistance against various mosquito species and are relatively cheaper, environmentally safer, biodegradable, easily accessible, and are non-toxic to non-targeted organisms. Therefore, in this review article, the current knowledge of phytochemical sources exhibiting larvicidal activity and their variations in response to solvents used for their extraction is underlined. Also, different methods such as physical, chemical, and biological for silver nanoparticle (AgNPs) synthesis, their mechanism of synthesis using plant extract, their potent larvicidal activity, and the possible mechanism by which these particles kill mosquito larvae are discussed. In addition, constraints related to commercialization of nanoherbal products at government and academic or research level and barriers from laboratory experiments to field trial have also been discussed. This comprehensive information can be gainfully employed for the development of herbal larvicidal formulations and nanopesticides against insecticide-resistant vector species in the near future.

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Fabrication and Characterization of Noble Crystalline Silver Nanoparticles from Ceropegia bulbosa Roxb Root Tuber Extract for Antibacterial, Larvicidal and Histopathology Applications

Cited by 14 publications

References 0 publications

Green synthesis of silver nanoparticles using aqueous rhizome extract of Zingiber officinale and Curcuma longa: In-vitro anti-cancer potential on human colon carcinoma HT-29 cells

Green synthesis of silver nanoparticles using aqueous rhizome extract of Zingiber officinale and Curcuma longa: In-vitro anti-cancer potential on human colon carcinoma HT-29 cells

Green synthesis of selenium nanoparticles mediated from Ceropegia bulbosa Roxb extract and its cytotoxicity, antimicrobial, mosquitocidal and photocatalytic activities

Biocontrol of mosquito vectors through herbal-derived silver nanoparticles: prospects and challenges

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