Fabrication and Characterization of Porous Diopside/Akermanite Ceramics with Prospective Tissue Engineering Applications

Nicoară, Adrian-Ionuţ; Alecu, Andrada Elena; Balaceanu, Gabriel-Costin; Puscasu, Maria-Eliza; Vasile, Bogdan Ștefan; Trușcă, Roxana

doi:10.3390/ma16165548

Cited by 5 publications

(1 citation statement)

References 38 publications

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“…Furthermore, compared to conventional phosphate-based bioceramics, silicate bioceramics offer a broader range of chemical compositions, which can contribute to optimizing various physicochemical properties, including mechanical strength, as well as biological attributes such as bioactivity and degradation [2]. Consequently, in recent years, particular attention has been paid to bioceramics based on materials like wollastonite (CaSiO 3 ), akermanite (Ca 2 MgSiO 7 ), diopside (CaMgSi 2 O 6 ), hardystonite (Ca 2 ZnSi 2 O 7 ), bredigite (Ca 7 MgSi 4 O 16 ), and merwinite (Ca 3 MgSi 2 O 8 ) [10][11][12][13][14]. Furthermore, the literature [3,[15][16][17][18][19][20][21][22][23] has highlighted the impact of other cations within these materials on biological behavior.…”

Section: Introductionmentioning

confidence: 99%

New 3D Printed Scaffolds Based on Walstromite Synthesized by Sol–Gel Method

Chiriac,

Popescu,

Pele

et al. 2024

JFB

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This study explores the potential utilization of walstromite (BaCa2Si3O9) as a foundational material for creating new bioceramics in the form of scaffolds through 3D printing technology. To achieve this objective, this study investigates the chemical–mineralogical, morphological, and structural characteristics, as well as the biological properties, of walstromite-based bioceramics. The precursor mixture for walstromite synthesis is prepared through the sol–gel method, utilizing pure reagents. The resulting dried gelatinous precipitate is analyzed through complex thermal analysis, leading to the determination of the optimal calcination temperature. Subsequently, the calcined powder is characterized via X-ray diffraction and scanning electron microscopy, indicating the presence of calcium and barium silicates, as well as monocalcium silicate. This powder is then employed in additive 3D printing, resulting in ceramic scaffolds. The specific ceramic properties of the scaffold, such as apparent density, absorption, open porosity, and compressive strength, are assessed and fall within practical use limits. X-ray diffraction analysis confirms the formation of walstromite as a single phase in the ceramic scaffold. In vitro studies involving immersion in simulated body fluid (SBF) for 7 and 14 days, as well as contact with osteoblast-like cells, reveal the scaffold’s ability to form a phosphate layer on its surface and its biocompatibility. This study concludes that the walstromite-based ceramic scaffold exhibits promising characteristics for potential applications in bone regeneration and tissue engineering.

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Section: Introductionmentioning

confidence: 99%

New 3D Printed Scaffolds Based on Walstromite Synthesized by Sol–Gel Method

Chiriac,

Popescu,

Pele

et al. 2024

JFB

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Zero-value dental mould waste: an innovative pathway for high purity calcium source enabling the production of akermanite ceramics

Mohd Rosli,

Baba Ismail

2024

J Aust Ceram Soc

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Modern Materials Used in the Reparative Regeneration of Bone Tissue of the Maxillofacial Region (Review)

Demyashkin,

Fidarov,

Ivanov

et al. 2024

Actual Problems in Dentistry

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An urgent problem of modern implantology remains the development of means and methods for restoring the integrity of bone tissue when defects occur. An important aspect of the problem remains the validity of the choice of osteoplastic material. Despite the fairly successful use of various types of osteoplastic materials in clinical implantology for the closure of small bone defects, the treatment of large diastases remains a subject of debate and requires further search and testing of various osteoplastic materials. Aim of the study: to analyze specialized scientific literature and describe the characteristics of the most common osteoplastic materials for replacing bone tissue defects. Methodology. This literature review was based on 63 sources from the following databases: PubMed, PubMed Central, Scopus, Medscape, Elibrary, ResearchGate, Google Scholar. Results. A description of osteoinductive materials used to replace bone defects in modern clinical practice is presented: ceramics, biocomposites based on them, corals, synthetic bones, mesenchymal stem cell cultures, 3D printing, etc. Emphasis is placed on the advantages and disadvantages of these methods. Conclusions. Based on the analysis of the literature, we can conclude that the problem of developing and introducing osteoplastic materials into clinical practice is a complex and multi-level area of joint activity of specialists in various fields. The most promising areas for further research are modifications of ceramic-based osteoplastic structures to increase their density, as well as additional cultivation of mesenchymal cells and 3D printing. However, these methods for replacing extensive bone tissue defects also need to be improved and new research conducted.

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Fabrication and Characterization of Porous Diopside/Akermanite Ceramics with Prospective Tissue Engineering Applications

Cited by 5 publications

References 38 publications

New 3D Printed Scaffolds Based on Walstromite Synthesized by Sol–Gel Method

New 3D Printed Scaffolds Based on Walstromite Synthesized by Sol–Gel Method

Zero-value dental mould waste: an innovative pathway for high purity calcium source enabling the production of akermanite ceramics

Modern Materials Used in the Reparative Regeneration of Bone Tissue of the Maxillofacial Region (Review)

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