Fabrication and characterization of SrAl2O4: Eu2+Dy3+/CS-PCL electrospun nanocomposite scaffold for retinal tissue regeneration

Sepahvandi, Azadeh; Eskandari, Mahnaz; Moztarzadeh, Fathollah

doi:10.1016/j.msec.2016.03.028

Cited by 35 publications

(17 citation statements)

References 31 publications

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“…In addition, the blending of PCL with other synthetic polymers with different properties for the preparation of polymer blends, after which the fabricated fillers can be introduced to the blends to afford PCL/blends composites with tremendous enhancement of the mechanical properties [79,83,84]. Table 4 summarizes the different solvent systems for electrospinning of PCL/filler nanocomposites and their mechanical properties [27,52,56,58,[62][63][64]67,72,80,82,[84][85][86][87][88][89]. Of all mechanical properties presented, modulus, tensile and strain, there was a discernible increase when the nanoclay is introduced at 1% and 5%.…”

Section: Mechanical Properties Of Electrospun Pcl and Its Compositesmentioning

confidence: 99%

Morphology and Properties of Electrospun PCL and Its Composites for Medical Applications: A Mini Review

et al. 2019

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Polycaprolactone (PCL) is one of the most used synthetic polymers for medical applications due to its biocompatibility and slow biodegradation character. Combining the inherent properties of the PCL matrix with the characteristic of nanofibrous particles, result into promising materials that can be suitable for different applications, including the biomedical applications. The advantages of nanofibrous structures include large surface area, a small diameter of pores and a high porosity, which make them of great interest in different applications. Electrospinning, as technique, has been heavily used for the preparation of nano- and micro-sized fibers. This review discusses the different methods for the electrospinning of PCL and its composites for advanced applications. Furthermore, the steady state conditions as well as the effect of the electrospinning parameters on the resultant morphology of the electrospun fiber are also reported.

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Section: Mechanical Properties Of Electrospun Pcl and Its Compositesmentioning

confidence: 99%

Morphology and Properties of Electrospun PCL and Its Composites for Medical Applications: A Mini Review

et al. 2019

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“…The accumulative release of cis- DIDP from the fiber was calculated as a function of the incubation time. In this paper, cis- DIDP was uniformly dispersed in the electrospinning solution and evenly scattered in the PCL fibers [27, 28]. Predetermined amount of cis- DIDP@PCL (~100 mg) was dissolved in 100 mL sustained-release solution.…”

Section: Methodsmentioning

confidence: 99%

Electrospun Poly(ε-caprolactone) Composite Nanofibers with Controlled Release of Cis-Diamminediiodoplatinum for a Higher Anticancer Activity

2017

Nanoscale Res Lett

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Poly(ε-caprolactone) (PCL) nanofibers were prepared by electrospun, on which the cis-diamminediiodoplatinum (cis-DIDP) was loaded, cis-DIDP@PCL, which effectively overcame cis-DIDP from dissociation or premature interaction with other bimolecular groups. Meanwhile, the toxicity and cross-resistance of cis-DIDP were reduced greatly. In vitro, cis-DIDP released from the PCL nanofibers eradicated the tumor cells around twice times more than free cis-DIDP, even better than cisplatin. Furthermore, cis-DIDP@PCL could controllably release cis-DIDP in different sustained-release solution based on our experiment.Electronic supplementary materialThe online version of this article (doi:10.1186/s11671-017-2092-y) contains supplementary material, which is available to authorized users.

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“…Sephavandi et al [ 116 ] developed a chondroitin sulphate poly(ɛ-caprolactone) CS-PCL copolymer 3-dimensional CS-PCL/PCL scaffold via grafting of ɛ-caprolactone onto chondroitin sulphate hydroxyl groups and combination with PCL for retinal tissue regeneration [ 117 ]. This polymer was combined with SrAl 2 O 4 : Eu 2 + , Dy 3+ nanoparticles which were prepared using a standard sol-gel method [ 118 ].…”

Section: Tissue Engineering and Regenerationmentioning

confidence: 99%

Bioactive Nanocomposites for Tissue Repair and Regeneration: A Review

Bramhill

Ross

2017

IJERPH

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This review presents scientific findings concerning the use of bioactive nanocomposites in the field of tissue repair and regeneration. Bioactivity is the ability of a material to incite a specific biological reaction, usually at the boundary of the material. Nanocomposites have been shown to be ideal bioactive materials due the many biological interfaces and structures operating at the nanoscale. This has resulted in many researchers investigating nanocomposites for use in bioapplications. Nanocomposites encompass a number of different structures, incorporating organic-inorganic, inorganic-inorganic and bioinorganic nanomaterials and based upon ceramic, metallic or polymeric materials. This enables a wide range of properties to be incorporated into nanocomposite materials, such as magnetic properties, MR imaging contrast or drug delivery, and even a combination of these properties. Much of the classical research was focused on bone regeneration, however, recent advances have enabled further use in soft tissue body sites too. Despite recent technological advances, more research is needed to further understand the long-term biocompatibility impact of the use of nanoparticles within the human body.

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Fabrication and characterization of SrAl2O4: Eu2+Dy3+/CS-PCL electrospun nanocomposite scaffold for retinal tissue regeneration

Cited by 35 publications

References 31 publications

Morphology and Properties of Electrospun PCL and Its Composites for Medical Applications: A Mini Review

Morphology and Properties of Electrospun PCL and Its Composites for Medical Applications: A Mini Review

Electrospun Poly(ε-caprolactone) Composite Nanofibers with Controlled Release of Cis-Diamminediiodoplatinum for a Higher Anticancer Activity

Bioactive Nanocomposites for Tissue Repair and Regeneration: A Review

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