Fabrication and characterization of thermoresponsive Fe3O4@PNIPAM hybrid nanomaterials by surface-initiated RAFT polymerization

Wang, Haodong; Luo, Wenqian; Chen, Jiucun

doi:10.1007/s10853-012-6493-0

Cited by 34 publications

(19 citation statements)

References 38 publications

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“…5 the HD of the PNIPAM-graed AOX50 and FK320 SiNPs in water suspensions have changed with increase in temperature and sudden decrease of the hydrodynamic diameter was observed at the LCST of the polymer. [34][35][36][37] This transition was observed at 32 C for AOX50-PNIPAM nanoparticles and at 31.6 C for FK320-PNIPAM nanoparticles.…”

Section: Characterization Of Pnipam-graed Nanoparticlesmentioning

confidence: 84%

Packed hybrid silica nanoparticles as sorbents with thermo-switchable surface chemistry and pore size for fast extraction of environmental pollutants

et al. 2018

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Section: Characterization Of Pnipam-graed Nanoparticlesmentioning

confidence: 84%

Packed hybrid silica nanoparticles as sorbents with thermo-switchable surface chemistry and pore size for fast extraction of environmental pollutants

et al. 2018

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“…Generally used as thermosensitive drug delivery and cell separation [79][80][81][82] Polyethylene-imine (PEI)…”

Section: Polymer Advantages and Applications Referencesmentioning

confidence: 99%

Gd-Doped Superparamagnetic Magnetite Nanoparticles for Potential Cancer Theranostics

Palihawadana-Arachchige¹,

Naik²,

Vaishnava³

et al. 2017

Nanostructured Materials - Fabrication to Applications

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Nanotechnology has facilitated the applications of a class of nanomaterials called superparamagnetic iron oxide nanoparticles (SPIONs) in cancer theranostics. This is a new discipline in biomedicine that combines therapy and diagnosis in one platform. The multifunctional SPIONs, which are capable of detecting, visualizing, and destroying the neoplastic cells with fewer side effects than the conventional therapies, are reviewed in this chapter for theranostic applications. The chapter summarizes the design parameters such as size, shape, coating, and target ligand functionalization of SPIONs, which enhance their ability to diagnose and treat cancer. The review discusses the methods of synthesizing SPIONs, their structural, morphological, and magnetic properties that are important for theranostics. The applications of SPIONs for drug delivery, magnetic resonance imaging, and magnetic hyperthermia therapy (MHT) are included. The results of our recent MHT study on Gd-doped SPION as a possible theranostic agent are highlighted. We have also discussed the challenges and outlook on the future research for theranostics in clinical settings.

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“…A wide range of organic and inorganic polymers have been applied to modify Fe 3 O 4 NPs (Díaz‐Álvarez, Turiel, & Martín‐Esteban, ; Ji, Qi, Li, & Wang, ; Prabha & Raj, ). The main interest of recent research is the surface functionality of Fe 3 O 4 NPs with polymeric shells because they have shown a high ability to control the chemical structure, composition and function of the polymers (Wang, Luo, & Chen, ). Since the surface features can be highly altered by selecting different functional monomers, surface functionalization by grafting of the polymer is one of the most effective methods available for preparing polymer‐coated NPs.…”

Section: Introductionmentioning

confidence: 99%

Employment of modified Fe₃O₄ nanoparticles using thermo‐sensitive polymer for extraction and pre‐concentration of cefexime in biological samples

Naghibi

Sahebi

2017

Biomedical Chromatography

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Cefexime is a useful antibiotic that can be prescribed to treat bacterial infections. Nanoparticles have been widely marketed as a universal solution among scientists. Many studies have been performed to modify nanoparticles to make them functional as extraction and pre-concentration agents and drug carriers. Temperature-sensitive polymers belong to a group of substances that undergo a major change in their physical features in response to temperature. Recently developed polymers can be used in many different areas, including modification of nanoparticles. In order to modify this nanoparticle, grafting copolymerization of Fe O nanoparticles was performed using poly (N-vinylcaprolactam) and 3-allyloxy-1,2-propanediol. The optimum conditions for pre-concentration of cefexime were studied. Under these optimum conditions, extraction recovery of biological samples in the range of 71-89% was obtained. The limit of detection and precision of proposed method were 4.5 × 10 μg mL and <4.11% (relative standard deviation), respectively. Based on the results from analysis of cefexime, in biological samples using the proposed method, the ability of this method to extract and pre-concentrate cefexime was confirmed. Also, satisfactory results from an in vitro study on drug release in simulated intestine media were obtained.

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Fabrication and characterization of thermoresponsive Fe3O4@PNIPAM hybrid nanomaterials by surface-initiated RAFT polymerization

Cited by 34 publications

References 38 publications

Packed hybrid silica nanoparticles as sorbents with thermo-switchable surface chemistry and pore size for fast extraction of environmental pollutants

Packed hybrid silica nanoparticles as sorbents with thermo-switchable surface chemistry and pore size for fast extraction of environmental pollutants

Gd-Doped Superparamagnetic Magnetite Nanoparticles for Potential Cancer Theranostics

Employment of modified Fe₃O₄ nanoparticles using thermo‐sensitive polymer for extraction and pre‐concentration of cefexime in biological samples

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Fabrication and characterization of thermoresponsive Fe3O4@PNIPAM hybrid nanomaterials by surface-initiated RAFT polymerization

Cited by 34 publications

References 38 publications

Packed hybrid silica nanoparticles as sorbents with thermo-switchable surface chemistry and pore size for fast extraction of environmental pollutants

Packed hybrid silica nanoparticles as sorbents with thermo-switchable surface chemistry and pore size for fast extraction of environmental pollutants

Gd-Doped Superparamagnetic Magnetite Nanoparticles for Potential Cancer Theranostics

Employment of modified Fe3O4 nanoparticles using thermo‐sensitive polymer for extraction and pre‐concentration of cefexime in biological samples

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Employment of modified Fe₃O₄ nanoparticles using thermo‐sensitive polymer for extraction and pre‐concentration of cefexime in biological samples