2011
DOI: 10.1080/00914037.2010.531808
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Fabrication and In Vitro Bioactivity of Poly (ϵ-caprolactone) Composites Filled with Silane-Modified Nano-Apatite Particles

Abstract: Silane coupling agents were firstly employed to modify the surfaces of nano-apatite (n-HA) particles, and then thin films of the silanized n-HA=PCL composites were successfully developed by incorporating solvent dispersion and thermal co-blending with hot-pressing methods. In vitro studies were conducted using the 2-time simulated body fluid (2SBF). Composite specimens were soaked in 2SBF from 3 to 14. Results showed that a layer of bone-like apatite was formed within 7 days on the surfaces of all composites, … Show more

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Cited by 10 publications
(4 citation statements)
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“…Therefore, agglomerated p-HA and c-HA can be easily broken down into smaller particle under the influence of shear force during the composite preparation. Additionally, there was a report in biomaterial applications that the homogeneous dispersion of HA in the polymer matrix can enhance protein adsorption and cell adhesion and proliferation due to the larger specific surface area of HA [12,28,29] .…”
Section: Characterization Of Pla Composites Morphological Properties mentioning
confidence: 97%
“…Therefore, agglomerated p-HA and c-HA can be easily broken down into smaller particle under the influence of shear force during the composite preparation. Additionally, there was a report in biomaterial applications that the homogeneous dispersion of HA in the polymer matrix can enhance protein adsorption and cell adhesion and proliferation due to the larger specific surface area of HA [12,28,29] .…”
Section: Characterization Of Pla Composites Morphological Properties mentioning
confidence: 97%
“…Polycaprolactone (PCL) is a promising candidate for scaffolding because it is FDA approved, is low-cost, but also has soft and flexible characteristics [25,26]. For these reasons, Aghdam et al [27] used PCL and PGA to construct a synthetic nanofibrous scaffold to culture cardiac progenitor cells.…”
Section: Scaffoldsmentioning
confidence: 99%
“…In an attempt to obtain improved mechanical properties of the BF=PLA composites, this preliminary study examines the use of chemical treatment utilizes silane that is known to enhance compatibility of inorganic fiber and polymer matrix [4][5][6] . Types of solvent and lengths of immersion time are the variables.…”
Section: Introductionmentioning
confidence: 99%