Fabrication of 3D printed modular microfluidic system for generating and manipulating complex emulsion droplets

Song, Ryungeun; Abbasi, Muhammad Salman; Lee, Jinkee

doi:10.1007/s10404-019-2258-2

Cited by 40 publications

(38 citation statements)

References 51 publications

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“…A top, intermediate and bottom module can be integrated through screw threads to produce double emulsions and multilayer fibers (Figure 8(3)). Song et al [94] also applied the similar modular design to achieve different functions including generation of single and double emulsions (Figure 8(4)).…”

Section: 3dp Droplet Microfluidicsmentioning

confidence: 99%

“…Thus droplet coalescence efficiency was enhanced in this way. Song et al [94] bonded electrodes on the droplet generation module (Figure 9(4)). In the presence of an external DC electric field, single emulsions can be deformed and coalesced, and double emulsions can be ruptured to release the inner core droplets.…”

Section: 3dp Droplet Microfluidicsmentioning

confidence: 99%

“…Male-female connectors with locking bump and O-rings connected each module. Reproduce of [77,82,92,94].…”

Section: Figurementioning

confidence: 99%

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Three-Dimensional Printed Devices in Droplet Microfluidics

Zhang

Duan

2019

Micromachines

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Droplet microfluidics has become the most promising subcategory of microfluidics since it contributes numerous applications to diverse fields. However, fabrication of microfluidic devices for droplet formation, manipulation and applications is usually complicated and expensive. Three-dimensional printing (3DP) provides an exciting alternative to conventional techniques by simplifying the process and reducing the cost of fabrication. Complex and novel structures can be achieved via 3DP in a simple and rapid manner, enabling droplet microfluidics accessible to more extensive users. In this article, we review and discuss current development, opportunities and challenges of applications of 3DP to droplet microfluidics.

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Section: 3dp Droplet Microfluidicsmentioning

confidence: 99%

Section: 3dp Droplet Microfluidicsmentioning

confidence: 99%

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Three-Dimensional Printed Devices in Droplet Microfluidics

Zhang

Duan

2019

Micromachines

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“…Recent EHD studies have explored more complex EHD interface topologies related to multiple phase emulsion droplets, and also covered the broader aspects, such as the emulsion instabilities, breakups, and particles manipulation at the emulsion interface forming novel colloidal assemblies [ 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ]. Though it has been almost six decades since the research in this area commenced, it is only until recently that a few studies pertaining to the droplet EHD with applicative prospects have been reported [ 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 ].…”

Section: Introductionmentioning

confidence: 99%

Electro-Hydrodynamics of Emulsion Droplets: Physical Insights to Applications

et al. 2020

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The field of droplet electrohydrodynamics (EHD) emerged with a seminal work of G.I. Taylor in 1966, who presented the so-called leaky dielectric model (LDM) to predict the droplet shapes undergoing distortions under an electric field. Since then, the droplet EHD has evolved in many ways over the next 55 years with numerous intriguing phenomena reported, such as tip and equatorial streaming, Quincke rotation, double droplet breakup modes, particle assemblies at the emulsion interface, and many more. These phenomena have a potential of vast applications in different areas of science and technology. This paper presents a review of prominent droplet EHD studies pertaining to the essential physical insight of various EHD phenomena. Here, we discuss the dynamics of a single-phase emulsion droplet under weak and strong electric fields. Moreover, the effect of the presence of particles and surfactants at the emulsion interface is covered in detail. Furthermore, the EHD of multi-phase double emulsion droplet is included. We focus on features such as deformation, instabilities, and breakups under varying electrical and physical properties. At the end of the review, we also discuss the potential applications of droplet EHD and various challenges with their future perspectives.

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“…The electric field effects on droplets and emulsions provide a versatile avenue for exploring the underlying fluid dynamic mechanisms and instabilities [ 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 ]. It has wide applications including targeted drug delivery [ 16 , 17 ], particle synthesis [ 18 ], material science [ 19 , 20 ], electrohydrodynamic atomization [ 21 ], particle manipulation [ 22 , 23 ] and producing unique colloidal assemblies [ 24 , 25 , 26 ]. The major stimulating force in these processes is the electric shear stresses that are generated due to the build-up of free electric charges at the interface that produce the interfacial flows [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Deformation of Emulsion Droplet with Clean and Particle-Covered Interface under an Electric Field

et al. 2020

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The electrohydrodynamic deformation of an emulsion droplet with a clean and particle-covered interface was explored. Here, the electrohydrodynamic deformation was numerically and experimentally demonstrated under the stimuli of moderate and strong electric fields. The numerical method involves the coupling of the Navier–Stokes equation with the level set equation of interface tracking and the governing equations of so-called leaky dielectric theory. The simulation model developed for a clean interface droplet was then extended to a capsule model for densely particle-covered droplets. The experiments were conducted using various combinations of immiscible oils and particle suspensions while the electric field strength ~105 V/m was generated using a high voltage supply. The experimental images obtained by the camera were post-processed using an in-house image processing code developed on the plat-form of MATLAB software. The results show that particle-free droplets can undergo prolate (deformation in the applied electric field direction) or oblate deformation (deformation that is perpendicular to the direction of the applied electric field) of the droplet interface, whereas the low-conductivity particles can be manipulated at the emulsion interface to form a ‘belt’, ‘helmet’ or ‘cup’ morphologies. A densely particle-covered droplet may not restore to its initial spherical shape due to ‘particle jamming’ at the interface, resulting in the formation of unique droplet shapes. Densely particle-covered droplets behave like droplets covered with a thin particle sheet, a capsule. The deformation of such droplets is explored using a simulation model under a range of electric capillary numbers (i.e., the ratio of the electric stresses to the capillary stresses acting at the droplet interface). The results obtained are then compared with the theory and experimental findings. It was shown that the proposed simulation model can serve as a tool to predict the deformation/distortion of both the particle-free and the densely particle-covered droplets within the small deformation limit. We believe that this study could provide new findings for the fabrication of complex-shaped species and colloidosomes.

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Fabrication of 3D printed modular microfluidic system for generating and manipulating complex emulsion droplets

Cited by 40 publications

References 51 publications

Three-Dimensional Printed Devices in Droplet Microfluidics

Three-Dimensional Printed Devices in Droplet Microfluidics

Electro-Hydrodynamics of Emulsion Droplets: Physical Insights to Applications

Deformation of Emulsion Droplet with Clean and Particle-Covered Interface under an Electric Field

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