Fabrication of agarose hydrogel with patterned silver nanowires for motion sensor

Han, Qingquan; Chen, Yang; Song, Wei; Zhang, Milin; Wang, Shengtao; Ren, Peng; Hao, Linna; Wang, Anhe; Yin, Jian

doi:10.1007/s42242-019-00051-w

Cited by 30 publications

(19 citation statements)

References 39 publications

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“…They are bendable, stretchable, and lightweight, enabling them to be conformally attached onto diverse complex surfaces. [ 1,2 ] Due to these distinct features, such high‐performance flexible devices including flexible pressure/strain sensor, [ 3,4 ] thermal sensor, [ 5 ] optical sensor, [ 6 ] or proximity sensor [ 7 ] have been widely applied in safe human–machine interaction, [ 8 ] environmental monitoring, [ 9 ] and healthcare management. [ 10 ]…”

Section: Introductionmentioning

confidence: 99%

“…They are bendable, stretch able, and lightweight, enabling them to be conformally attached onto diverse complex surfaces. [1,2] Due to these distinct fea tures, such highperformance flexible devices including flexible pressure/strain sensor, [3,4] thermal sensor, [5] optical sensor, [6] units, and 1 proximity sensor unit. The bottom electrode layer (BEL) of this sensor sheet, as the kernel of structural design, is efficiently utilized and can be reconfigured as a plate of pressuresensitive capacitors, thermistors, or a selfcapacitance proximity sensor.…”

Section: Introductionmentioning

confidence: 99%

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A Fully Printed Flexible Sensor Sheet for Simultaneous Proximity–Pressure–Temperature Detection

Luo

Pang

et al. 2021

Adv Materials Technologies

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or proximity sensor [7] have been widely applied in safe human-machine interac tion, [8] environmental monitoring, [9] and healthcare management. [10] Unlike conventional sensor platforms that deliver one or two sensing function alities by separate devices, multimodal sensors endeavor to integrate multiple physical or chemical perceptions into a single device, and thus endow individuals with superior intelligence and interac tivity. [11] For instance, Jung et al. demon strated a flexible sensor array capable of detecting pressure and temperature based on piezoresistive and thermoelectric effects, respectively. [12] Temperature and pressure sensing arrays are separated by an insulating film to ensure independent measurements. Similar functions were achieved in a more delicate fingertip shaped resistive sensor, [13] where mate rial tuning and strain isolation reduced coupling between measured variables. To further promote the versatility of sensors, Zhao et al. integrated strain, pressure, and proximity percep tions into a stretchable capacitor array, realizing contact and noncontact interactions. [14] In addition, multiple sensory modal ities were also applied in plant growth management. Takei et al. proposed a flexible sensor sheet mainly based on ZnIn 2 S 4 nanosheets for optical, humidity, and temperature measure ments. [15] Nevertheless, additional efforts should be made to bypass relatively complicated fabrications accompanied by intri cate 3D structures. [13,14,16,17] Printing methods are considered as a versatile category of fabrication technologies to realize functional flexible elec tronics, including screen printing, inkjet printing and dispenser printing, etc. Their merits of customized prototyping, facile manufacturing steps and scalable fabrication [18,19] are prom ising to overcome the sophisticated fabrications for multimodal sensors. Besides, most printing technologies rely on human friendly functional inks rather than hazard chemicals [20,21] (e.g., photoresists or etchants in photolithography). Therefore, the printingbased scheme is environmentfriendly and has the potential to massively produce intelligent multimodal sensors for daily applications.To extend the functionality of multimodal sensors while maintaining facile fabrication processes and overall perfor mance after integration, a trimodal sensor sheet that can be fully manufactured by printing technologies is proposed. It integrates 4 × 4 pressure sensor units, 2 × 2 temperature sensor Flexible multimodal sensors are an indispensable part of Internet of Things for human-machine interfaces, health monitoring, and soft robots. Despite tremendous research efforts dedicated to high sensitivity, flexibility, and multifunctionality, these merits are conventionally accompanied with sophisticated fabrications that hinder practical applications. Herein, a fully printed flexible trimodal sensor sheet containing 4 × 4 pressure sensor units, 2 × 2 temperature sensor units, and 1 proximity sensor unit is proposed. Its elaborate structure featured by a...

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Fully Printed Flexible Sensor Sheet for Simultaneous Proximity–Pressure–Temperature Detection

Luo

Pang

et al. 2021

Adv Materials Technologies

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“…The PC12 cell line was purchased from Cell Bank of the Chinese Academy of Science (Shanghai, China, Catalog #: TCR9), which are highly differentiated already. PDMS is a commonly used elastomer due to its good biocompatibility and mechanical properties, and Ag-based materials have inherently high electrical conductivity ( Han et al, 2019 ). PC12 cells are widely used to study neural behavior since they could differentiate into the nerve cells, which have neurite, dendrite, and axon, and form synapses with neighboring cells to build neural networks ( Foley et al, 2005 ).…”

Section: Methodsmentioning

confidence: 99%

Effect of Electrical and Electromechanical Stimulation on PC12 Cell Proliferation and Axon Outgrowth

Liu

et al. 2021

Front. Bioeng. Biotechnol.

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Peripheral nerve injuries have become a common clinical disease with poor prognosis and complicated treatments. The development of tissue engineering pointed a promising direction to produce nerve conduits for nerve regeneration. Electrical and mechanical stimulations have been incorporated with tissue engineering, since such external stimulations could promote nerve cell proliferation, migration and differentiation. However, the combination of electrical and mechanical stimulations (electromechanical stimulation) and its effects on neuron proliferation and axon outgrowth have been rarely investigated. Herein, silver nanowires (AgNWs) embedded polydimethylsiloxane (PDMS) electrodes were developed to study the effects of electromechanical stimulation on rat pheochromocytoma cells (PC12 cells) behaviors. AgNWs/PDMS electrodes demonstrated good biocompatibility and established a stable electric field during mechanical stretching. PC12 cells showed enhanced proliferation rate and axon outgrowth under electrical stimulation alone, and the cell number significantly increased with higher electrical stimulation intensity. The involvement of mechanical stretching in electrical stimulation reduced the cell proliferation rate and axon outgrowth, compared with the case of electrical stimulation alone. Interestingly, the cellular axons outgrowth was found to depend on the stretching direction, where the axons prefer to align perpendicularly to the stretch direction. These results suggested that AgNWs/PDMS electrodes provide an in vitro platform to investigate the effects of electromechanical stimulation on nerve cell behaviors and can be potentially used for nerve regeneration in the future.

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“…The agarose hydrogels are used as an electroactive material [64] Fabrication of agarose hydrogel with patterned silver nanowires for motion sensor Wearable sensor for human motion detection [158] Controlling surface-induced platelet activation by agarose and gelatin-based hydrogel films Controlling platelet-surface activation [159] Silk fibroin Marginal sealing around integral bilayer scaffolds for repairing osteochondral defects based on photocurable silk hydrogels Methacrylic silk fibroin sealant loaded with TGF-𝛽3 promotes chondrocyte migration and differentiation [138] Stretchable silk fibroin hydrogels A stretchable and tough silk fibroin hydrogels [160] Impacts of blended bombyx mori silk fibroin and recombinant spider silk fibroin hydrogels on cell growth Improve cell activities and affect cell growth [161] The innate immune response of self-assembling silk fibroin hydrogels Quantify the hemocompatibility and inflammatory response of silk fibroin hydrogels [162] Nanocellulose Robust versatile nan cellulose/polyvinyl alcohol/carbon dot hydrogels for biomechanical sensing…”

Section: Polymerization Monomers Of the Synthetic Polymer Hydrogelsmentioning

confidence: 99%

An Overview on Recent Progress of the Hydrogels: From Material Resources, Properties, to Functional Applications

Wang

Yang

et al. 2022

Macromol. Rapid Commun.

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Hydrogels, as the most typical elastomer materials with three-dimensional (3D) network structures, have attracted wide attention owing to their outstanding features in fields of sensitive stimulus response, low surface friction coefficient, good flexibility, and bio-compatibility. Because of numerous fresh polymer materials (or polymerization monomers), hydrogels with various structure diversities and excellent properties are emerging, and the development of hydrogels is very vigorous over the past decade. This review focuses on state-of-the-art advances, systematically reviews the recent progress on construction of novel hydrogels utilized several kinds of typical polymerization monomers, and explores the main chemical and physical cross-linking methods to develop the diversity of hydrogels. Following the aspects mentioned above, the classification and emerging applications of hydrogels, such as pH response, ionic response, electrical response, thermal response, biomolecular response, and gas response, are extensively summarized. Finally, this review is done with the promises and challenges for the future evolution of hydrogels and their biological applications.

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Fabrication of agarose hydrogel with patterned silver nanowires for motion sensor

Cited by 30 publications

References 39 publications

A Fully Printed Flexible Sensor Sheet for Simultaneous Proximity–Pressure–Temperature Detection

A Fully Printed Flexible Sensor Sheet for Simultaneous Proximity–Pressure–Temperature Detection

Effect of Electrical and Electromechanical Stimulation on PC12 Cell Proliferation and Axon Outgrowth

An Overview on Recent Progress of the Hydrogels: From Material Resources, Properties, to Functional Applications

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