2018
DOI: 10.1021/acsami.7b18493
|View full text |Cite
|
Sign up to set email alerts
|

Fabrication of BSA@AuNC-Based Nanostructures for Cell Fluoresce Imaging and Target Drug Delivery

Abstract: Drug delivery which can offer efficient and localized drug transportation together with imaging capabilities is highly demanded in the development of cancer theranostic approaches. Herein, we report the construction of bovine serum albumin (BSA) gold nanoclusters (BSA@AuNCs) for cell fluoresce imaging and target drug delivery. BSA@AuNCs were modified with cyclic arginine-glycine-aspartate with the product RGD-BSA@AuNCs to enhance cell internalization of the nanoclusters. Furthermore, doxorubicin hydrochloride … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
50
0

Year Published

2019
2019
2023
2023

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 91 publications
(50 citation statements)
references
References 38 publications
0
50
0
Order By: Relevance
“…BSA is a common material used to synthesize nanoparticles due to its novel biological activity. 72,73 Especially, BSA-based nanomaterials are widely applied in biomedicine for their good properties of drug load. For example, doughnut-shaped BSA nanoparticles loaded with doxorubicin are utilized to overcome multidrug resistance during cancer treatment.…”
Section: Mes Modication Enhances the Antiviral Activity Of Te/ Bsa Nmentioning
confidence: 99%
“…BSA is a common material used to synthesize nanoparticles due to its novel biological activity. 72,73 Especially, BSA-based nanomaterials are widely applied in biomedicine for their good properties of drug load. For example, doughnut-shaped BSA nanoparticles loaded with doxorubicin are utilized to overcome multidrug resistance during cancer treatment.…”
Section: Mes Modication Enhances the Antiviral Activity Of Te/ Bsa Nmentioning
confidence: 99%
“…[28] For example, multiplex identification of bacteria by their inherited binding affinities with bacteria, [29] rapid detection of insulin by their enhanced functionality, [30,31] and tumor imaging by their unique emission wavelength. [31] But these applications often require high PL intensity, the relatively low PL intensity (usually lower than 6%) still existing in BSA-AuNCs extremely limits their developments. This is mainly because how reaction factors participate in the formation process and affect the optical properties of BSA-AuNCs is still unclear.…”
Section: Doi: 101002/ppsc201900314mentioning
confidence: 99%
“…This green synthesis method give BSA‐AuNCs unique physicochemical properties, improving their prospects for biological applications . For example, multiplex identification of bacteria by their inherited binding affinities with bacteria, rapid detection of insulin by their enhanced functionality, and tumor imaging by their unique emission wavelength . But these applications often require high PL intensity, the relatively low PL intensity (usually lower than 6%) still existing in BSA‐AuNCs extremely limits their developments.…”
Section: Introductionmentioning
confidence: 99%
“…Furthermore, bovine serum albumin (BSA) has received more attention than other biological carrier, especially in cancer treatment because of their unique properties [8]. Rarely toxicity or immunogenicity; biodegradable; stable in circulation; qualifying a long half-life; does not require surfactants or polymeric materials for preparation; easy access to all tumour sites via the blood circulation; high chemical stability; and convenient to administer are likely properties to persuade researcher to use Albumin eagerly.…”
Section: Introductionmentioning
confidence: 99%