Fabrication of Carbohydrate Chips Based on Polydopamine for Real-Time Determination of Carbohydrate–Lectin Interactions by QCM Biosensor

Shang, Kun; Song, Siyu; Cheng, Ying-Sheng; Guo, Lili; Pei, Yuxin; Lv, Xiaomeng; Aastrup, Teodor; Pei, Zhichao

doi:10.3390/polym10111275

Cited by 12 publications

(13 citation statements)

References 44 publications

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“…Thus, new materials must be found with strong adhesion for modifying energetic crystal particles. Recently, mussel coatings inspired by dopamine in situ polymerization attracted interest and are usually used to passivate large amounts of substrates such as glass, metals, polymers, and nano-carbon materials [18][19][20][21][22][23][24][25]. Dopamine chemistry was reported for crystal modification of energetic materials, such as HMX, RDX, and 1,3,5-triamino-2,4,6-trinitrobenzene (TATB) [11,[26][27][28].…”

Section: Introductionmentioning

confidence: 99%

Enhanced Crystal Stabilities of ε-CL-20 via Core-Shell Structured Energetic Composites

et al. 2020

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2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20) is a widely used high-energy explosive for the application of energetic materials. However, the phase transformation from ε-CL-20 to γ-CL-20 restrains its further application in polymer bonded explosives (PBXs) and propellants. To inhibit the phase transition of CL-20, dopamine was first used in an efficient and facile method of in situ polymerization to passivate CL-20 crystals. The core-shell microcapsule particles were obtained, and the morphological characterization demonstrates the formation of a dense core-shell structure. The differential scanning calorimetry (DSC) and in situ X-ray diffraction (XRD) test results show that the compact and dense coating delays the ε-CL-20 crystal transformation temperature by about 30 °C, which enhances thermal stability. In addition, with the coating via polymers, the friction sensitivity of ε-CL-20 crystals decreases significantly. The findings indicate a successful application of dopamine chemistry in high-energy explosives, which provides an attractive method to modify the properties of CL-20 crystals.

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Section: Introductionmentioning

confidence: 99%

Enhanced Crystal Stabilities of ε-CL-20 via Core-Shell Structured Energetic Composites

et al. 2020

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“…Up until now, mussel-inspired coating with the in-situ polymerization of dopamine has raised increasing interest and has been frequently used to coat various substrates, such as glass, metal, polymer, and nanocarbon materials [20,21,22,23,24,25,26,27,28]. Recently, there have been some reports on the application of dopamine chemistry to energetic crystal processing, such as HMX, hexanitrohexaazaisowurtzitane (CL-20), and 1,3,5-triamino-2,4,6-trinitrobenzene (TATB) [29,30,31].…”

Section: Introductionmentioning

confidence: 99%

Core-Shell Structured HMX@Polydopamine Energetic Microspheres: Synergistically Enhanced Mechanical, Thermal, and Safety Performances

et al. 2019

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The solid–solid phase transition, poor mechanical properties, and high sensitivity has impeded further practical applications of 1,3,5,7-tetranitro-1,3,5,7-tetrazocane (HMX) based polymer bonded explosives (PBXs). To address these issues together, a facile and effective route was employed to achieve a coating of polydopamine (PDA) on the surface of explosive crystals via in situ polymerization of dopamine. Additionally, PBXs based on HMX@PDA microcapsules were prepared with a fluoropolymer as polymer binder. Improved storage modulus, static mechanical strength and toughness, and creep resistance has been achieved in as-prepared PDA modified PBXs. The β-δ phase transition temperature of as-obtained PBXs based on conventional HMX (C-HMX)@PDA was improved by 16.3 °C. The friction sensitivity of the C-HMX based PBXs showed a dramatic drop after the PDA coating. A favorable balance proposed in this paper among thermal stability, mechanical properties, and sensitivity was achieved for C-HMX based PBXs with the incorporation of PDA.

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“…The use of sensory materials in physiological media with medical applications has been a topical issue during the last years [ 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 ]. Thus, we propose herein an indirect quantification of protease activity from the quantitative detection of amino acids using sensory films.…”

Section: Introductionmentioning

confidence: 99%

Why Is the Sensory Response of Organic Probes within a Polymer Film Different in Solution and in the Solid-State? Evidence and Application to the Detection of Amino Acids in Human Chronic Wounds

et al. 2020

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We anchored a colourimetric probe, comprising a complex containing copper (Cu(II)) and a dye, to a polymer matrix obtaining film-shaped chemosensors with induced selectivity toward glycine. This sensory material is exploited in the selectivity detection of glycine in complex mixtures of amino acids mimicking elastin, collagen and epidermis, and also in following the protease activity in a beefsteak and chronic human wounds. We use the term inducing because the probe in solution is not selective toward any amino acid and we get selectivity toward glycine using the solid-state. Overall, we found that the chemical behaviour of a chemical probe can be entirely changed by changing its chemical environment. Regarding its behaviour in solution, this change has been achieved by isolating the probe by anchoring the motifs in a polymer matrix, in an amorphous state, avoiding the interaction of one sensory motif with another. Moreover, this selectivity change can be further tuned because of the effectiveness of the transport of targets both by the physical nature of the interface of the polymer matrix/solution, where the target chemicals are dissolved, for instance, and inside the matrix where the recognition takes place. The interest in chronic human wounds is related to the fact that our methods are rapid and inexpensive, and also considering that the protease activity can correlate with the evolution of chronic wounds.

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Fabrication of Carbohydrate Chips Based on Polydopamine for Real-Time Determination of Carbohydrate–Lectin Interactions by QCM Biosensor

Cited by 12 publications

References 44 publications

Enhanced Crystal Stabilities of ε-CL-20 via Core-Shell Structured Energetic Composites

Enhanced Crystal Stabilities of ε-CL-20 via Core-Shell Structured Energetic Composites

Core-Shell Structured HMX@Polydopamine Energetic Microspheres: Synergistically Enhanced Mechanical, Thermal, and Safety Performances

Why Is the Sensory Response of Organic Probes within a Polymer Film Different in Solution and in the Solid-State? Evidence and Application to the Detection of Amino Acids in Human Chronic Wounds

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