Fabrication of micropores on titanium implants using femtosecond laser technology: Perpendicular attachment of connective tissues as a pilot study

Abdal‐hay, Abdalla; Staples, Reuben; Alhazaa, Abdulaziz; Fournier, Benjamin; Al‐Gawati, Mahmoud A.; Lee, Ryan SB; Ivanovski, Sašo

doi:10.1016/j.optlastec.2021.107624

Cited by 17 publications

(12 citation statements)

References 29 publications

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“…Although this method allowed inspection of fluorescently labeled components, its limitation was that it couldn’t obtain high-resolution images of ultrastructural features such as hemidesmosomes. On the other hand, in a very recent study analyzing the perpendicular attachment of connective tissues, with confocal laser scanning microscopy it was demonstrated that the fibroblasts had attached and proliferated over the entire micropore surface, forming a prolific cell sheet and also, 3D imaging (confocal z-stacking) confirmed the migration of cells into the micropore structures [ 63 ]. In our study, where autofluorescence was employed, similar observations were made when recombining the “thick” sections in 3D ( Videofile No.…”

Section: Discussionmentioning

confidence: 99%

Influence of Section Thickness on the Accuracy and Specificity of Histometric Parameters Using Confocal Laser Scanning Microscopy in a Canine Model of Experimental Peri-Implantitis—A Proof of Concept

Boldeanu

Popa-Wagner

Boariu

et al. 2023

JCM

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Objectives: Tissue breakdown was assessed by confocal laser scanning microscopy (CLSM) using autofluorescence around implants with ligatures, on a dog hemimandible. Influence of section thickness on the accuracy of histometrical observations was also evaluated, in comparison with thin sections in light microscopy. Material and Methods: Three months after tooth extraction, implants were placed. Two months after abutment placement, ligatures were placed with no plaque control. 11 months post-implantation, the animal was sacrificed. Undecalcified thin (30 µm) sections were cut, stained and evaluated by light microscopy to be used as a reference. Additional sections were performed, so that another pair of unstained thick sections resulted (250–300 µm). Tissue loss was assessed using histomorphometric parameters under CLSM and was compared to the light microscopy reference ones. Results: Morphometry confirmed tissue loss more pronounced on the “thick” and quick sections, when compared to the time-consuming and technique-sensitive “thin” ones. Conclusions: Within the limits of the present study, the adequacy of histometrical observations under CLSM reveal commensurable information about soft-tissue-bone-implant details, when compared to traditional light microscopy histological protocols. The CLSM investigation may seem demanding, yet the richness of data acquired may justify this approach, provided seatbacks caused by improper manipulation of “thick” sections are avoided.

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Section: Discussionmentioning

confidence: 99%

Influence of Section Thickness on the Accuracy and Specificity of Histometric Parameters Using Confocal Laser Scanning Microscopy in a Canine Model of Experimental Peri-Implantitis—A Proof of Concept

Boldeanu

Popa-Wagner

Boariu

et al. 2023

JCM

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“…The study of these parameters in the case of titanium modifications is very important due to the use of titanium in biomedicine. The evaluation of the roughness parameter is important because an increase in this index has a positive effect on the cell adhesion during osseointegration and on the connection between the bone and an implant [49]. The use of titanium and its alloys in biomedicine is indicated for the manufacture of artificial hip joints, artificial knee joints, bone plates, fracture fixation screws, prosthetic heart valves, pacemakers, and the production of artificial hearts [50,51].…”

Section: Roughness and Wettabilitymentioning

confidence: 99%

Influence of Laser Modification on the Surface Character of Biomaterials: Titanium and Its Alloys—A Review

Sypniewska

Szkodo

2022

Coatings

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Laser surface modification is a widely available and simple technique that can be applied to different types of materials. It has been shown that by using a laser heat source, reproducible surfaces can be obtained, which is particularly important when developing materials for medical applications. The laser modification of titanium and its alloys is advantageous due to the possibility of controlling selected parameters and properties of the material, which offers the prospect of obtaining a material with the characteristics required for biomedical applications. This paper analyzes the effect of laser modification without material growth on titanium and its alloys. It addresses issues related to the surface roughness parameters, wettability, and corrosion resistance, and discusses how laser modification changes the hardness and wear resistance of materials. A thorough review of the literature on the subject provides a basis for the scientific community to develop further experiments based on the already investigated relationships between the effects of the laser beam and the surface at the macro, micro, and nano level.

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“…Titanium alloys are highly favored in aerospace, medical and marine sectors [1]. It has excellent qualities, such as sufficient strength and hardness at high temperatures, corrosion resistance and low density [2]. Titanium grade 5 exhibits excellent tensile strength at room temperature, the resistance to fatigue and crack propagation is also exceptional.…”

Section: Introductionmentioning

confidence: 99%

Experimental investigation on fiber laser micro drilling of Titanium grade 5: fabrication, nature-inspired optimization and analysis through image processing

Kar,

Goswami

2024

Eng. Res. Express

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This investigation showed that micro holes were created on Titanium grade 5 substrate surface using a 30 W fiber laser. The impact of the control factors such as scan speed, frequency, number of passes and power were studied on the responses namely heat affected zone (HAZ), hole circularity (HC) and deviation in diameter (DIV). The control factors were optimized using firefly algorithm. Mathematical models were developed for each response having significant R-square value. 3D surface plots were used to examine how the control parameters affected the response. The firefly algorithm identifies the optimal conditions for micro drilling as scan speed of 210 mm/s, frequency of 40 kHz, power of 8 W and total of 40 passes which improved experimental findings i.e. HC-0.974, DIV-37.02 µm and HAZ-19.53. After comparing the predicted values with the experimental findings, it was observed that the prediction error is lowest for HC (1.23 %) followed by DIV (13.9 %) and HAZ (16.9 %). Image processing technique was used to convert regular images into a digital format to extract useful information.

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Fabrication of micropores on titanium implants using femtosecond laser technology: Perpendicular attachment of connective tissues as a pilot study

Cited by 17 publications

References 29 publications

Influence of Section Thickness on the Accuracy and Specificity of Histometric Parameters Using Confocal Laser Scanning Microscopy in a Canine Model of Experimental Peri-Implantitis—A Proof of Concept

Influence of Section Thickness on the Accuracy and Specificity of Histometric Parameters Using Confocal Laser Scanning Microscopy in a Canine Model of Experimental Peri-Implantitis—A Proof of Concept

Influence of Laser Modification on the Surface Character of Biomaterials: Titanium and Its Alloys—A Review

Experimental investigation on fiber laser micro drilling of Titanium grade 5: fabrication, nature-inspired optimization and analysis through image processing

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