“…It is known that Fe3O4-NPs which have super paramagnetic properties, can be synthesized from abundant iron sand minerals in Indonesia, this material has broad application prospects, such as: biocompatible [1], biosensing [2], contras agent for MRI system [3], Drug Delivary System [4], absorbent heavy-metal (Cr, Pb, Ag) [5], [6]. The same thing for SiO2-NPs has inert properties which are good insulators and are not easy to react with chemical compounds, high porosity, low thermal conductive; can be synthesized from quartz sand, and organic materials of ricehusk ash, baggase-ash which is abundantly available in Indonesia; SiO2-NPs has a wide range of applications, such as: anti-aging material [7], divice-optoelectronic [8], coating anticorrosion [9], DDS [10], cosmetic [11], water-filter system [12], adsoption for hevy-metal [10], [13], packaging system [11], etc.…”