Fabrication of Nanoemulsions by Microfluidization

Villalobos-Castillejos, Fidel; Granillo-Guerrero, Virginia G.; Leyva-Daniel, Diana E.; Alamilla‐Beltrán, Liliana; Gutiérrez-López, Gustavo F.; Monroy-Villagrana, A.; Jafari, Seid Mahdi

doi:10.1016/b978-0-12-811838-2.00008-4

Cited by 30 publications

(23 citation statements)

References 82 publications

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“…Microfluidization methods have been used to produce food ingredient nanoemulsions (Goh et al, 2015; Zhang et al, 2015). Microfluidization techniques produce food grade nanoemulsions with uniform droplet size distributions and greater stabilities (Villalobos-Castillejos et al, 2018).…”

Section: Formulation Techniques Of Nanoemulsion Drug Delivery Systemsmentioning

confidence: 99%

Techniques for Formulation of Nanoemulsion Drug Delivery System: A Review

Kumar

Bishnoi

Shukla

et al. 2019

pnf

296

120

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Nanoemulsion drug delivery systems are advanced modes for delivering and improving the bioavailability of hydrophobic drugs and the drug which have high first pass metabolism. The nanoemulsion can be prepared by both high energy and low energy methods. High energy method includes high-pressure homogenization, microfluidization, and ultrasonication whereas low energy methods include the phase inversion emulsification method and the self-nanoemulsification method. Low energy methods should be preferred over high energy methods as these methods require less energy, so are more efficient and do not require any sophisticated instruments. However high energy methods are more favorable for food grade emulsion as they require lower quantities of surfactant than low energy methods. Techniques for formulation of nanoemulsion drug delivery system are overlapping in nature, especially in the case of low energy methods. In this review, we have classified different methods for formulation of nanoemulsion systems based on energy requirements, nature of phase inversion, and self-emulsification.

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Section: Formulation Techniques Of Nanoemulsion Drug Delivery Systemsmentioning

confidence: 99%

Techniques for Formulation of Nanoemulsion Drug Delivery System: A Review

Kumar

Bishnoi

Shukla

et al. 2019

pnf

296

120

View full text Add to dashboard Cite

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“…Spray drying is a technique used for the microencapsulation of microorganisms (Peighambardoust et al, 2011;Broeckx et al, 2016) and volatile compounds (Sultana et al, 2018;Turasan et al, 2015;Lasekan and Otto, 2009;Villalobos-Castillejos et al, 2017) with the aim of protecting them during storage. Many works have been performed to protect Lactobacillus spp.…”

Section: Introductionmentioning

confidence: 99%

MICROENCAPSULATION OF MICROBIAL CONSORTIUM AND VOLATILE COMPOUNDS OF PALM (Acrocomia aculeata) WINE

Luján-Hidalgo¹,

México²,

Rustrian-Castellanos³

et al. 2018

Rev.Mex.Ing.Quim.

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“…The size of the protein aggregates decreased as the number of MF cycles increased, independently of the pH used to form the SPI aggregates. This was indicative that the number of MF cycles did not induce reaggregation of small particles into larger ones due to excess input of energy caused by the application of cycles or pressure over a threshold value (Villalobos-Castillejos et al, 2018). The largest particle sizes were found at pH 5, which is close to the isoelectric point (IP) of the proteins of the SPI (4.5) where an increase in protein aggregation was expected due to the charge balance of the amino acids is close to zero and the interaction with water molecules decreased, which provoked a decrement in protein solubility at this pH (González-Cruz et al, 2020;Achouri et al, 2005).…”

Section: Particle Size (Ps) and Polydispersity Index (Pdi)mentioning

confidence: 99%