Fabrication of perforated polyethylene microfiltration membranes for circulating tumor cells separation by thermal nanoimprint method

Tang, Feiyi; Shao, Ziming; Ni, Mengyang; Cui, Yushuang; Yuan, Changsheng; Ge, Haixiong

doi:10.1007/s00339-018-2343-5

Cited by 9 publications

(6 citation statements)

References 20 publications

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“…The pore size and thickness of the produced PCL film were 21 nm and 5 x 10 9 pore cm -1 , correspondingly. This methodology creates layers with a broad range of pore diameters and thicknesses, that has been used in a variety of applications, such as tumour cell separation [20], nanoparticle exhibit fabrication [21], and biosensing [22].…”

Section: Other Soft Lithography Methodsmentioning

confidence: 99%

Porous Membrane and their Applications

Swain

2022

Advanced Functional Membranes

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Porous membranes have several uses in separation technology. This chapter basically explored various fabrication routes of different types of porous membranes and their applications in industrial and biomedical fields. The urgent need of a low cost perfect membrane needs to be optimised with good mechanical strength, chemical resistance, and thermal stability. This chapter focuses on producing porous polymeric/ceramic membranes with nano/submicron holes using block copolymer self-assembly, track etching, 3D printing, nanoimprinting, lithography, and electrospinning, etc. Porous polymeric/ceramic membranes are used in separation techniques in various industries, drug administration, bioseparation, and biosensing. The effect of membrane material, pore shape and size towards the membrane performance for various technological challenges are thoroughly discussed.

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Section: Other Soft Lithography Methodsmentioning

confidence: 99%

Porous Membrane and their Applications

Swain

2022

Advanced Functional Membranes

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“…Therefore, membrane separation based on size sieving has been developed as a substitute strategy because it is nondisruptive, inexpensive and quick. Overall, there are three routes for the fabrication of a microporous membrane: track etching, photolithography and thermal nanoimprinting [152] , [153] , [154] , [155] , [156] . Track etching method needs a highly accelerated heavy ion.…”

Section: In Vitro Blood Diagnosismentioning

confidence: 99%

“…For such cases, thermal nanoimprints have been developed to address these deficiencies. In the work of Tang et al [156] , a polyethylene membrane was sandwiched between a Ni mold and a glass substrate. Then, this sandwiched stack was pressed by a nanoimprint machine to obtain a microporous membrane.…”

Section: In Vitro Blood Diagnosismentioning

confidence: 99%

Membranes for the life sciences and their future roles in medicine

Yao

Liu

Chu

et al. 2022

Chinese Journal of Chemical Engineering

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“…This type of device facilitates rapid isolation of CTCs without the need for labelling. The developed method achieved an average capture efficiency of 84% for lung cancer cells spiked into blood samples [73]. Although this method is attractive, the isolated CTCs are mostly impure or of mixed origin owing to the heterogeneity of cancer cells.…”

Section: Ctc Technologiesmentioning

confidence: 99%

Circulating tumour cells: a broad perspective

Akpe

Brown

Cock

2020

J. R. Soc. Interface.

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Circulating tumour cells (CTCs) have recently been identified as valuable biomarkers for diagnostic and prognostic evaluations, as well for monitoring therapeutic responses to treatments. CTCs are rare cells which may be present as one CTC surrounded by approximately 1 million white blood cells and 1 billion red blood cells per millilitre of peripheral blood. Despite the various challenges in CTC detection, considerable progress in detection methods have been documented in recent times, particularly for methodologies incorporating nanomaterial-based platforms and/or integrated microfluidics. Herein, we summarize the importance of CTCs as biological markers for tumour detection, highlight their mechanism of cellular invasion and discuss the various challenges associated with CTC research, including vulnerability, heterogeneity, phenotypicity and size differences. In addition, we describe nanomaterial agents used for electrochemistry and surface plasmon resonance applications, which have recently been used to selectively capture cancer cells and amplify signals for CTC detection. The intrinsic properties of nanomaterials have also recently been exploited to achieve photothermal destruction of cancer cells. This review describes recent advancements and future perspectives in the CTC field.

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Fabrication of perforated polyethylene microfiltration membranes for circulating tumor cells separation by thermal nanoimprint method

Cited by 9 publications

References 20 publications

Porous Membrane and their Applications

Porous Membrane and their Applications

Membranes for the life sciences and their future roles in medicine

Circulating tumour cells: a broad perspective

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