Fabrication of the Antibiotic Sensor by the Multifunctional Stable Adjustable Luminescent Lanthanide Metal–Organic Frameworks

Abstract

In recent years, the irrational use of antibiotics has become very widespread. It is necessary to regulate this phenomenon through antibiotic detection. In this work, a series of isomorphic Ln-MOFs (Ln = Tb3+ and Eu3+) were synthesized from 1,3,5-tri(4-carboxyphenyl)benzene (H3L) and Ln3+ by the solvothermal method for the first time. A series of 1-Eu x Tb 1–x with different luminescence were doped by changing the molar ratio of Tb3+ and Eu3+. Ln3+ forms a 4-connected 2D network structure through self-assembly with fully deprotonated L3–. It shows good chemical stability in water, and its luminescence is not affected by aqueous solutions with different pH values. 1-Eu demonstrates rapid and sensitive detection capabilities for MDZ and TET with good recyclability and low detection limits (10–5). In order to increase the practicability of 1-Eu, two portable sensors have been prepared, in which the fluorescent film (Film@1-Eu) has a detection limit of 10–4, and the sensitivity is only less than 10% of the titration results. A portable fluorescent test paper can reach the detection limit of 14.7 ppm. This study provides a new idea for the application of stable multifunctional materials in the field of fluorescence sensing.

Decoding the Mechanistic Strategies of Lanthanide‐based Luminescent Metal‐Organic Frameworks towards Antibiotic Detection

“…Adapted with permission. [109] Copyright 2023, American Chemical Society. c) The photoluminescence spectra of Tb-L1 for various amounts of TC (Inset: corresponding optical images photographed under ultraviolet lamp.…”

“…The photophysical and photochemical attributes of H 3 BTB were further explained by synthesizing an isomorphic MOF very recently for the detection of MDZ and TC. [109] The technique was extended to the fabrication of film and paper strips based on the probe material for practical applications as shown in Figure 5b. A remarkable competition in the absorption of excitation energy through IFE by the analytes and the probe at the same wavelength was noticed which caused the attenuation of fluorescence.…”

“…b) Schematic representation of Eu-MOF for antibiotic sensing. Adapted with permission [109]. Copyright 2023, American Chemical Society.…”

Construction of a Sensitive Fluorescence Sensor for Convenient 1-HP and UA Detection Relied on a Stable Eu-MOF

“…Compared with the traditional methods for 1-hydroxypyrene and uric acid detection, such as high-performance liquid chromatography, mass spectrometry, electrochemical sensor technologies, and colorimetric method, which are constrained to their insuperable deficiencies including expensive instruments, intricate pretreatment processes, nonreal-time detection, − chemical sensors constructed from metal–organic frameworks (MOFs) have received extensive attention profited from their fascinating advantages: simple synthesis, modifiable structure, high selectivity, and real-time detection. − Among the MOFs, lanthanide-centered MOFs (Ln-MOFs) feature the attractive superiorities combining the Ln­(III) ions with MOFs, such as high specific surface area, adjustable pore volume, characteristic luminescence emission, long lifetimes, and high quantum yields. , In virtue of these charming properties, fluorescent probes relied on Ln-MOFs have been extensively developed and devoted to sensing various substances, including metal ions, − anions, − amino acids, − antibiotics, − biomarkers, − etc.…”

Colorimetric Response and Real-Field Recognition of Organo-toxins and Antibiotics in Aqueous Medium Using a 2D Coordination Polymer

“…Antibiotics are important medicines that are frequently prescribed to humans, animals, and plants in order to recover from infection and illness . However, the long-time consumption of antibiotics leads to resistance to antibiotic activity, which is even more harmful. , On the other hand, mismanagement of antibiotics can lead to the deposition of their residue in water and soil and finally impact our ecosystem .…”