Facile and novel electrochemical preparation of a graphene–transition metal oxide nanocomposite for ultrasensitive electrochemical sensing of acetaminophen and phenacetin

Abstract

A facile and novel preparation strategy based on electrochemical techniques for the fabrication of electrodeposited graphene (EGR) and zinc oxide (ZnO) nanocomposite was developed. The morphology and structure of the EGR-based nanocomposite were investigated by scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (XPS) and Raman spectroscopy. Meanwhile, the electrochemical performance of the nanocomposite was demonstrated with cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Due to the synergistic effect of EGR and ZnO nanoparticles, an ultrasensitive electrochemical sensor for acetaminophen (AC) and phenacetin (PCT) was successfully fabricated. The linearity ranged from 0.02 to 10 μM for AC and 0.06 to 10 μM for PCT with high sensitivities of 54,295.82 μA mM(-1) cm(2) for AC and 21,344.66 μA mM(-1) cm(2) for PCT, respectively. Moreover, the practical applicability was validated to be reliable and desirable in pharmaceutical detections. The excellent results showed the promise of the proposed preparation strategy of EGR-transition metal oxide nanocomposite in the field of electroanalytical chemistry.

Cauliflower‐like Platinum Particles Decorated Reduced Graphene Oxide for Sensitive Determination of Acetaminophen

“…According to the equation (2), the slope is calculated to be 0.666 which indicates that the oxidation of ACTM on the PtÀ RGO/GCE is a combination of diffusion and adsorption controlled process. This result is found to be in good agreement with those reported literature [13,46]. Also, it was reported that the number of electrons (n) taking part in the oxidation process can be calculated according to the equation [43] below:…”

Giant piezoresistivity in aligned carbon nanotube nanocomposite: account for nanotube structural distortion at crossed tunnel junctions

“…[1][2][3][4][5] Compared with the conventional piezoresistive sensing materials, such as metals, alloys, and inorganic semiconductor materials, sensors made of multifunctional CNT/polymer composites are lightweight, compact, mechanically durable and easily conformable for desired shapes and applications. For instance, they can be directly embedded in structural composites to provide real-time internal strain sensing for structural health monitoring.…”

Dispersion of multi-walled carbon nanotubes in [BMIM]PF 6 for electrochemical sensing of acetaminophen

“…The linear range obtained for the proposed sensor is similar of others reported modified electrodes. The LOD obtained in this work is higher than the modified electrode with graphene [56,63] and Nano-TiO2 [48], however the proposed sensor exhibit lower LOD value than other modified electrodes which could confirm that fMWCNT- [BMIM]PF6/GCE have high electrocatalytic and surface effects. Therefore, the fMWCNT- [BMIM]PF6/GCE showed sensitivity up to 40 times higher when compared to ACOP sensors modified with metallic nanoparticles [62] for the determination of ACOP.…”