Facile determination of the degree of modification of ordered mesoporous silica by liquid phase NMR

Quantitative and convenient protocol for analysis of surface‐modified silica nanoparticles using 29Si‐NMR and near‐infrared diffuse reflection spectroscopy

“…Characterizations of the silanol and alkyl groups on the silica particle surface have been performed by various methods, for example, potentiometric titration with sodium hydroxide, 8 reaction with methyl lithium followed by gas chromatography, 9 labeling with chlorosilanes for X-ray photoelectron spectroscopy (XPS), 10,11 deuterium substitution for mass spectroscopy, 12 dissolution with NaOD or CsF for liquid-phase 1 H-nuclear magnetic resonance (NMR), [13][14][15] and thermogravimetric analysis (TGA). 5,6,10,11,15,16 These methods, however, are destructive, need pretreatment, and are often disturbed by adsorbed water.…”